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HIV Drug Resistance Early Warning Indicators in Namibia for Public Health Action

By Jonas Anna, Gweshe Justice, Siboleka Milner, DeKlerk Michael, Gawanab Michael, Badi Alfons, Sumbi Victor, Pereko Dawn, Blom Abraham, Mwinga Samson, Jordan Michael R., Jerger Logan, Lau Kiger and Hong Steven Y.

Abstract

HIV drug resistance (HIVDR) testing is not routinely available in many resource-limited settings, therefore antiretroviral therapy (ART) program and site factors known to be associated with emergence of HIVDR should be monitored to optimize the quality of patient care and minimize the emergence of preventable HIVDR.Records allowed reporting on three of the five selected EWIs. 22 of 33 (67%) sites met the target of 100% initiated on appropriate first-line regimens. 17 of 33 (52%) sites met the target of ≤20% LTFU. 15 of 33 (45%) sites met the target of 0% switched to a second-line regimen.EWI monitoring directly resulted in public health action which will optimize the quality of care, specifically the strengthening of ART record systems, engagement of ART sites, and operational research for improved adherence assessment and ART patient defaulter tracing

Publisher: Public Library of Science
Year: 2013
DOI identifier: 10.1371/journal.pone.0065653
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