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Harnessing copper-palladium alloy tetrapod nanoparticle-induced pro-survival autophagy for optimized photothermal therapy of drug-resistant cancer

By Yunjiao Zhang, Rui Sha, Lan Zhang, Wenbin Zhang, Peipei Jin, Weiguo Xu, Jianxun Ding, Jun Lin, Jing Qian, Guangyu Yao, Rui Zhang, Fanchen Luo, Jie Zeng, Jie Cao and Long-ping Wen

Abstract

“Conventional chemotherapy-photothermal therapy combination has limited efficacy in drug resistant cancers. Here they develop Copper-palladium tetrapod nanoparticles to overcome these challenges and show them to work in synergy with autophagy inhibitors to treat drug resistant cancers

Topics: Science, Q
Publisher: Nature Publishing Group
Year: 2018
DOI identifier: 10.1038/s41467-018-06529-y
OAI identifier: oai:doaj.org/article:1628584346614edca6b507729673b83f
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