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Management of Intensive Care Unit of the Case with Toxic Epidermal Necrolysis

By Tamer Kuzucuoğlu and Hülya Yiğit Özay


Toxic epidermal necrolysis (TEN) is a severe autoimmune idiosyncratic reaction, which is mostly caused by drugs, involves for more than 30% of the body surface and affects the entire mucosa, and is characterized by extensive epidermal loss. The worldwide incidence of TEN is estimated to be 0.4-1.3 million. The mortality rate of TEN is between 30-50%, and primary death cause is septicemia and multiple organ failure. The Scorten Mortality Scoring is widely used in assay of mortality and morbidity and gives substantially correct results. Since lesions are similar with burns and the possibility of sepsis in TEN, their follow-up in the burn intensive care unit (BICU) is widely accepted. In this case report, a 30-year-old male patient who developed TEN on the third day of cefuroxime axetil oral use due to upper respiratory tract infection was presented in the BICU follow-up, in company with the literature data

Topics: Epidermal necrolysis, toxic, sepsis, intensive care, SCORTEN Mortality Scale, Nikolsky’s sign, Dermatology, RL1-803
Publisher: Galenos Yayinevi
Year: 2018
DOI identifier: 10.4274/tdd.2338
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