Polarisation of metastasising cancer cells in circulation has not been investigated before. Here the authors identify single cell polarity as a distinct polarisation state of single cells in liquid phase, and show that perturbing single cell polarity affects attachment, adhesion, transmigration and metastasis in vitro and in vivo

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oai:doaj.org/article:e550a620f8de40bf90963e8198015b9eLast time updated on 6/4/2019

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