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Development of a periprosthetic joint infection by Abiotrophia defectiva years after total knee arthroplasty

By BS Trevor R. Tooley, MD Matthew P. Siljander and MD Michael Hubers


A 74-year-old male presented with acute right knee pain and inability to ambulate. The patient had a total knee arthroplasty, previously complicated by a periprosthetic femur fracture requiring surgical fixation and subsequent methicillin-resistant Staphylococcus epidermidis periprosthetic joint infection treated via two-stage revision. Cultures from knee fluid aspiration were positive for Abiotrophia defectiva. Identification was confirmed using matrix-assisted laser desorption ionization–time of flight mass spectrometry. The patient underwent a two-stage revision. Between stages, the patient received intravenous ceftriaxone for six weeks with subsequent normalization of inflammatory markers. Diagnosis of periprosthetic joint infection with identification of the organism is important to guide appropriate treatment. Keywords: Periprosthetic joint infection, Abiotrophia defectiva, Total knee arthroplast

Topics: Orthopedic surgery, RD701-811
Publisher: Elsevier
Year: 2019
DOI identifier: 10.1016/j.artd.2018.12.002
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