HSV1 transcripts exhibit differential subcellular localisation.
Abstract
HFFF cells grown in slide chambers were infected with Wt virus at a multiplicity of 2, fixed at 2, 4, 6, 8 or 12 hours after infection, and processed for mRNA FISH with probes to the IE transcripts, ICP27 and ICP0, the E transcript TK and the late transcripts vhs and gC (all in red). Nuclei were counterstained with DAPI (blue). Scale bar = 20 μm.</p- Image
- Figure
- Microbiology
- Cell Biology
- Molecular Biology
- Ecology
- Immunology
- Science Policy
- Infectious Diseases
- Virology
- Environmental Sciences not elsewhere classified
- Biological Sciences not elsewhere classified
- Chemical Sciences not elsewhere classified
- retention
- Δ22-
- cell transcriptome
- proteins HSV 1 encodes
- bind VP 16
- HSV 1 infection
- v irion h ost
- host
- mRNA
- virus transcriptome
- Wt infection
- herpes simplex virus 1
- translational shutoff
- VP 22
- mechanism
- vhs endoribonuclease activity
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This paper was published in FigShare.
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