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Correlation between antibody neutralization and binding to progressively more receptor-triggered forms of the same HIV-1 Env.

By Branislav Ivan (6236873), Zhaozhi Sun (6236876), Harini Subbaraman (6236879), Nikolas Friedrich (2435614) and Alexandra Trkola (51210)

Abstract

<p>Correlation between antibody neutralization and binding to progressively more receptor-triggered forms of the same HIV-1 Env.</p

Topics: Biophysics, Cell Biology, Immunology, Cancer, Infectious Diseases, Virology, Chemical Sciences not elsewhere classified, entry intermediates, CD 4 occupancy, HR, antibody epitope presentation, coreceptor binding site, conformation, neutralizing antibody activity, bnAb, CD 4 occupancy triggers sequential pre-fusion, immunodeficiency virus type 1, Env trimer, CD 4. Exposure, antibody dissociation rates, HIV, Escalating CD 4, CD 4 engagement, post-CD 4 engagement, CD 4-triggered Env
Year: 2019
DOI identifier: 10.1371/journal.pbio.3000114.t001
OAI identifier: oai:figshare.com:article/7597271
Provided by: FigShare
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