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Intravenous immunoglobulin treatment in chronic inflammatory demyelinating polyneuropathy

By P.A. (Pieter) van Doorn

Abstract

Patients with a chronic inflammatory demyelinating polyneuropathy (CIDP) may respond to\ud treatment with corticosteroids and to plasmapheresis, which was demonstrated in controlled\ud clinical studies. In an uncontrolled study it was found that 13/17 CIDP patients had a rapid and clinical\ud important improvement after infusion of Fresh Frozen Plasma (FFP). A beneficial response was\ud also seen after-mtravenous rmmunoglobulin (Mg) treatment. \ud The aims of this study were:\ud - to evaluate the clinical effectiveness of Mg in CIDP patients,\ud - to define clinical and inrmunological factors associated with improvement after Mg in CIDP\ud patients and - to investigate immunological mechanisms involved in the response to Mg treatment

Topics: chronic inflammatory demyelinating polyneuropathy, CIDP, treatment, corticosteroids, plasmapheresis, Fresh Frozen Plasma, FFP
Year: 1990
OAI identifier: oai:repub.eur.nl:50836

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