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Antifungal compounds of Xylaria sp., an endophytic fungus isolated from Palicourea marcgravii (Rubiaceae)

By Mariana C. Cafêu, Geraldo H. Silva, Helder L. Teles, Vanderlan da S. Bolzani, Ângela R. Araújo, Maria Cláudia M. Young and Ludwig H. Pfenning


Five compounds, 2-hexyl-3-methyl-butanodioic acid (1), cytochalasin D (2), 7-dechlorogriseofulvin (3), cytochalasin B (4) and griseofulvin (5), have been isolated from the endophytic fungus Xylaria sp., and their structures were elucidated on the basis of spectroscopic data. In the bioautography assay against Cladosporium cladosporioides and Cladosporium sphaerospermum, compounds 1 and 2 were found to be active while compounds 3, 4 and 5 did not show antifungal activity

Topics: endophytic fungus, Xylaria sp., antifungal compounds
Publisher: Sociedade Brasileira de Química
Year: 2005
OAI identifier: oai:scielo:S0100-40422005000600011
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