Location of Repository

Iron Acquisition from Transferrins by Campylobacter jejuni

By Claire Elizabeth Miller


Iron acquisition is vital for intestinal colonisation by Campylobacter jejuni. Characterisation of a number of iron uptake systems has occurred recently, allowing advancement in the understanding of the iron sources that C. jejuni utilises and how this occurs; however, the molecular basis of iron uptake from host iron-binding glycoproteins, the transferrins, is not known. The research presented here confirms that C. jejuni can use iron from the transferrins for growth and further characterises this process and the factors involved.\ud Iron uptake from the transferrins requires proximity and appears to be receptor specific. Binding of lactoferrin to the cell surface is iron-responsive. Cj0178, a protein similar to TonB-dependent receptors, is required and the involvement of the enterochelin outer membrane receptor protein CfrA, FeoB, the ferrous iron inner membrane transporter, and the ABC transporter system Cj0175c-Cj0173c was also indicated. Less lactoferrin bound to cells without Cj0178 and complementation of the cj0178 mutation was successful. A role for Cj0178 in the uptake of haem was not demonstrated. Regulation of the genes cj0176c-cj0173c and cj0177-tonB1 was shown to require Fur and promoter activity levels increased under iron-restriction. The presence of two Fur-boxes indicated separate regulation of the operons. The catecholamine stress hormone noradrenaline augmented the growth of C. jejuni in the absence and presence of iron and in the presence of the transferrins, but was non-essential.\ud A model is proposed of how transferrin-bound iron is used by C. jejuni. The process appears to be novel, involving a number of systems, but further work is required to confirm how they interact. The system through which noradrenaline may supply iron was investigated; however the mechanisms involved require further characterisation. The involvement of Cj0178 implies that the uptake of transferrin-derived iron is important for successful colonisation, which is vital for establishing an infection

Publisher: University of Leicester
Year: 2009
OAI identifier: oai:lra.le.ac.uk:2381/9918

Suggested articles



  1. (2002). A component of innate immunity prevents bacterial biofilm development.
  2. (1987). A demographic survey of Campylobacter, Salmonella,
  3. (1997). A genetic locus involved in iron utilization unique to some Campylobacter strains.
  4. (2006). A major role for FeoB in Campylobacter jejuni ferrous ion acquisition, gut colonization, and intracellular survival.
  5. (2000). A method for direct cloning of Fur-regulated genes: Identification of seven new Fur-regulated loci in Escherichia coli.
  6. (1988). A new heat-labile cytolethal distending toxin (CLDT) produced by Campylobacter spp.
  7. (1992). A novel DNA-binding protein with regulatory and protective roles in starved Escherichia coli.
  8. (1997). A novel non-heme iron-binding ferritin related to the DNA-binding proteins of the Dps family in Listeria innocua.
  9. (1994). A PCR-based strategy for the rapid construction of defined bacterial deletion mutants.
  10. (2001). A phase-variable capsule is involved in virulence of Campylobacter jejuni 81-176.
  11. (1985). A point-source outbreak of campylobacteriosis associated with consumption of raw milk.
  12. (1983). A rapid alkaline extraction method for the isolation of plasmid DNA.
  13. (1979). A rapid alkaline lysis procedure for screening recombinant plasmid DNA.
  14. (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.
  15. (2002). A small RNA regulates the expression of genes involved in iron metabolism in Escherichia coli.
  16. (1997). A small, stable RNA induced by oxidative stress: Role as a pleiotropic regulator and antimutator.
  17. (2007). ABC transporters: How small machines do a big job.
  18. (2001). ABC-transporter mediated uptake of iron, siderophores, heme and vitamin B12.
  19. (2001). Acquisition of iron from human transferrin by Porphyromonas gingivalis: A role for Arg- and Lysgingipan activities.
  20. (2003). Acquisition of siderophores in Gram-negative bacteria.
  21. (1998). Activation of the OxyR transcription factor by reversible disulfide bond formation.
  22. (1972). Acute enteritis due to related vibrio: first positive stool cultures.
  23. (1989). Adhesion to HeLa cells of Campylobacter jejuni and C. coli outer membrane components.
  24. (1992). Adrenergic control of motor and secretory function in the gastrointestinal tract.
  25. (2004). Adrenergic modulation of Escherichia coli O157:H7 adherence to the colonic mucosa.
  26. (1986). Aerobactin biosynthesis and transport genes of plasmid
  27. (1978). Amino acid biosynthesis and its regulation.
  28. (1989). An alkyl hydroperoxide reductase induced by oxidative stress in Salmonella typhimurium and Escherichia coli: Genetic characterization and cloning of ahp.
  29. (1996). An environmentally regulated pilus-like appendage involved in Campylobacter pathogenesis.
  30. (1971). An enzyme-based theory of obligate anaerobiosis: The physiological function of superoxide dismutase.
  31. (1993). An exploratory analysis of medication utilization in a medical intensive care unit.
  32. (1966). An iron-binding protein common to many external secretions.
  33. (1999). An iron-regulated alkyl hydroperoxide reductase (AhpC) confers aerotolerance and oxidative stress resistance to the microaerophilic pathogen Campylobacter jejuni.
  34. (1956). An unusual variant of acute idiopathic polyneuritis (syndrome of ophthalmoplegia ataxia and areflexia).
  35. (2000). Anatomy and physiology of the enteric nervous system.
  36. (2005). Anionindependent iron coordination by the Campylobacter jejuni ferric binding protein.
  37. (2000). Antibodies, directed towards Campylobacter jejuni antigens, in sera from poultry abattoir workers.
  38. (1987). Antigenic variation of Campylobacter flagella.
  39. (2002). Antiviral activity of ovotransferrin discloses an evolutionary strategy for the defensive activities of lactoferrin.
  40. (2006). Are happy chickens safer chickens? Poultry welfare and disease susceptibility.
  41. (1991). Assay of metabolic superoxide production in Escherichia coli.
  42. (1998). Bacillus subtilis contains multiple Fur homologues: identification of the iron uptake (Fur) and peroxide regulon (PerR) repressors.
  43. (1998). Bacterial fitness and plasmid loss: the importance of culture conditions and plasmid size.
  44. (2000). Bacterial heme sources: the role of heme, hemoprotein receptors and hemophores.
  45. (2003). Bacterial iron homeostasis.
  46. (1998). Bacterial lactoferrin receptors.
  47. (1999). Bacterial secreted proteins are required for the internalization of Campylobacter jejuni into cultured mammalian cells.
  48. (1996). Bacterial transferrin and lactoferrin receptors.
  49. Bactericidal properties of Campylobacter jejuni specific immunoglobulin M antibodies in commercial immunoglobulin preparations.
  50. (2004). Balancing acts: Molecular control of mammalian iron metabolism.
  51. (1996). Binding and surface exposure characteristics of the gonococcal transferrin receptor are dependent on both transferrinbinding proteins.
  52. (1998). Binding of hemehemopexin complexes by soluble HxuA protein allows utilization of this complexed heme by Haemophilus influenzae.
  53. (1998). Binding of the Fur (ferric uptake regulator) repressor of Escherichia coli to arrays of the GATAAT sequence.
  54. (2004). Biochemical and physical properties of siderophores.
  55. (1985). Biotypes and serotypes of thermophilic campylobacters isolated from cattle, sheep and pig offal and other red meats.
  56. (2007). Blockade of catecholamineinduced growth by adrenergic and dopaminergic receptor antagonists in Escherichia coli O157:H7, Salmonella enterica and Yersinia enterocolitica.
  57. (2000). Campylobacter contamination of raw meat and poultry at retail sale: Identification of multiple types and comparison with isolates from human infection.
  58. (1977). Campylobacter enteritis: a 'new' disease.
  59. (1992). Campylobacter helveticus' sp. nov., a new thermophilic group from domestic animals: characterization of the species and cloning of a species-specific DNA probe.
  60. (2000). Campylobacter infections in developing countries.
  61. (1999). Campylobacter jejuni - an emerging food borne pathogen.
  62. (1988). Campylobacter jejuni and Campylobacter hyointestinalis in the intestinal tract and on the carcasses of calves and cattle.
  63. (1998). Campylobacter jejuni bacteremia in human immunodeficiency virus (HIV)-infected and non-HIV-infected patients: Comparison of clinical features and review.
  64. (1999). Campylobacter jejuni contains two Fur homologs: characterization of iron-responsive regulation of peroxide stress defense genes by the PerR repressor.
  65. (1998). Campylobacter jejuni cytolethal distending toxin causes a G2-phase cell cycle block.
  66. (2005). Campylobacter jejuni gene expression in response to iron limitation and the role of Fur.
  67. (2005). Campylobacter jejuni inhibits the absorptive transport functions of Caco-2 cells and disrupts cellular tight junctions.
  68. (1995). Campylobacter jejuni motility and invasion of Caco-2 cells.
  69. (1988). Campylobacter jejuni subsp. doylei subsp. nov., a subspecies of nitrate-negative campylobacters isolated from human clinical specimens.
  70. (1998). Campylobacter species and GuillainBarré syndrome.
  71. (2000). Campylobacter toxins and their role in pathogenesis.
  72. (1998). Campylobacter upsaliensis: waiting in the wings.
  73. (1992). Catecholamine induced growth of Gram-negative bacteria.
  74. (2001). Catecholamine inotropes are growth factors for Staphylococcus epidermidis and other coagulase-negative staphylococci.
  75. (2006). Catecholate receptor proteins in Salmonella enterica: Role in virulence and implications for vaccine development.
  76. (1992). Characteristics of the internalization and intracellular survival of Campylobacter jejuni in human epithelial cells.
  77. (1990). Characterization and description of "Campylobacter upsaliensis" isolated from human feces.
  78. (1998). Characterization and gene sequencing of a 19-kDa periplasmic protein of Campylobacter jejuni/coli.
  79. (1996). Characterization of Campylobacter upsaliensis fur and its localization in a highly conserved region of the Campylobacter genome.
  80. (1993). Characterization of the ferrous iron uptake system of Escherichia coli.
  81. Characterization of the Plesiomonas shigelloides genes encoding the heme iron utilization system.
  82. (1995). Characterization of transferrin binding proteins 1 and 2 in invasive type b and nontypeable strains of Haemophilus influenzae.
  83. (1981). Citrate-dependent iron transport system in Escherichia coli K-12.
  84. (2000). Clinical aspects of Campylobacter infection.
  85. (2000). Clinical significance of Campylobacter and related species other than Campylobacter jejuni and C.
  86. (2001). Cloning and characterization of a Campylobacter jejuni iron-uptake operon.
  87. (1993). Cloning and characterization of Neisseria meningitidis genes encoding the transferrin-binding proteins
  88. (1998). Cloning and characterization of the fur gene from Helicobacter pylori.
  89. (1997). Cloning and functional characterization of Neisseria gonorrhoeae tonB, exbB and exbD genes.
  90. (1995). Cloning and transcription regulation of the Ferric Uptake Regulatory gene of Campylobacter jejuni TGH9011.
  91. (1994). Cloning, nucleotide sequence and characterization of a gene encoding superoxide dismutase from Campylobacter jejuni and Campylobacter coli.
  92. (1992). Cloning, sequencing and transcriptional regulation of the Vibrio cholerae fur gene.
  93. (1994). Cloning, sequencing, and expression of the Escherichia coli cytolethal distending toxin genes.
  94. (2006). Cofacial heme binding is linked to dimerization by a bacterial heme transport protein.
  95. (1988). Cohort study of intestinal infection with Campylobacter in Mexican children. Lancet i,
  96. (1998). Colicins-exocellular lethal proteins of Escherichia coli.
  97. (1994). Colicins: Structures, modes of action, transfer through membranes, and evolution.
  98. Colonization of chicks by motility mutants of Campylobacter jejuni demonstrates the importance of flagellin A expression.
  99. (1988). Colonization of gastrointestinal tracts of chicks by Campylobacter jejuni.
  100. (1985). Comparison of four hippurate hydrolysis methods for identification of thermophilic Campylobacter spp.
  101. (1991). Complete sequence of the Campylobacter jejuni glyA gene encoding serine hydroxymethyltransferase.
  102. (2001). Computation-directed identification of OxyR DNA binding sites in Escherichia coli.
  103. (1988). Confirmation of the Fur operator site by insertion of a synthetic oligonucleotide into an operon fusion plasmid.
  104. (1999). Conformation and selfassociation of human recombinant transforming growth factor-B3 in aqueous solutions.
  105. (1978). Constitutive expression of the iron-enterochelin and ferrichrome uptake systems in a mutant strain of Salmonella typhimurium.
  106. (1996). Construction of a ferritin-deficient mutant of Campylobacter jejuni: Contribution of ferritin to iron storage and protection against oxidative stress.
  107. (1996). Contribution of TonB- and Feo-mediated iron uptake to growth of Salmonella typhimurium in the mouse.
  108. (1990). Control of Escherichia coli superoxide dismutase (sodA and sodB) genes by the ferric uptake regulation (fur) locus.
  109. (1996). Cooperative interactions between the amino- and carboxyl -terminal lobes contribute to the unique iron-binding stability of lactoferrin.
  110. (1995). Coordinate regulation of Bacillus subtilis peroxide stress genes by hydrogen peroxide and metal ions.
  111. (1993). Coordinate regulation of siderophore and exotoxin A production: Molecular cloning and sequencing of the Pseudomonas aeruginosa fur gene.
  112. (1999). Copurification of the FpvA ferric pyoverdin receptor of Pseudomonas aeruginosa with its iron-free ligand: Implications for siderophore-mediated iron transport.
  113. (2003). Coupled degradation of a small regulatory RNA and its mRNA targets in Escherichia coli.
  114. (1999). Crystal structure of the outer membrane active transporter FepA from Escherichia coli.
  115. (1987). Current protocols in molecular biology.
  116. (1997). Cysteineto-alanine replacements in the Escherichia coli SoxR protein and the role of the [2Fe-2S] centers in transcriptional activation.
  117. (1988). Damage to the outer membrane of enteric Gram-negative bacteria by lactoferrin and transferrin.
  118. (1975). Demonstration of a capsule on Neisseria gonorrhoeae.
  119. (2006). dependent ferric iron transport in Campylobacter jejuni.
  120. (1991). Description of Campylobacter upsaliensis sp. nov. previously known as the CNW group.
  121. (1992). Detection of Campylobacter upsaliensis in diarrheic dogs and cats, using a selective medium with cefoperazone.
  122. (2005). Development and application of an insertional system for gene delivery and expression in Campylobacter jejuni.
  123. (1999). Differential iron transport into phagosomes isolated from RAW264.7 macrophage cell lines transfected with
  124. (1992). Differentiated Caco-2 cells as a model for enteric invasion by Campylobacter jejuni and C.
  125. (1989). Direct clone characterization from plaques and colonies by the polymerase chain reaction.
  126. (1994). Diseases due to Campylobacter, Helicobacter and related bacteria.
  127. (2001). DNA microarray-mediated transcriptional profiling of the Escherichia coli response to hydrogen peroxide.
  128. (2002). DNA sequence and mutational analyses of the pVir plasmid of Campylobacter jejuni 81-176.
  129. (2001). Do human bile salt stimulated lipase and colipase-dependent pancreatic lipase share a common heparin-containing receptor?
  130. (1990). Effect of glycolipids of Leishmania parasites on human monocyte activity: Inhibition by lipophosphoglycan.
  131. (2008). Effect of norepinephrine on colonisation and systemic spread of Salmonella enterica in infected animals: Role of catecholate siderophore precursors and degradation products.
  132. (1985). Effect of oral antibiotics and bacterial overgrowth on the translocation of the GI tract microflora in burned rats.
  133. (2005). Effect of RyhB small RNA on global iron use in Escherichia coli.
  134. (1998). Effect of siderophores, catecholamines, and catechol compounds on Listeria spp. growth in iron-complexed medium.
  135. (1987). Effects of serum carrier proteins on the growth of pathogenic Neisseriae with heme-bound iron.
  136. (1979). Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications.
  137. (2001). Emerging strategies in microbial haem capture.
  138. (1987). Endonuclease IV of Escherichia coli is induced by paraquat.
  139. (2007). Energy-coupled outer membrane transport proteins and regulatory proteins.
  140. (1995). Enterochelin acquisition in Campylobacter coli: Characterization of components of a binding-protein-dependent transport system.
  141. (1991). Epidemiology of Campylobacter enteritis.
  142. (2000). Epidemiology of Campylobacter jejuni infections in the United States and other industrialized nations.
  143. (1993). Escherichia coli K-12 ferrous iron uptake mutants are impaired in their ability to colonize the mouse intestine.
  144. (2001). Evidence for a genetically stable strain of Campylobacter jejuni.
  145. (1999). Evidence for a system of general protein glycosylation in Campylobacter jejuni.
  146. (2000). Evidence of an unusually long operator for the Fur repressor in the aerobactin promoter of Escherichia coli.
  147. (1988). Experimental Campylobacter jejuni infection in humans.
  148. (1972). Experiments in molecular genetics:
  149. (2002). Export of the siderophore enterobactin in Escherichia coli: Involvement of a 43 kDa membrane exporter.
  150. (1982). Expression of a high-affinity mechanism for acquisition of transferrin iron by Neisseria meningitidis.
  151. (1999). Extracellular iron reductases: Identification of a new class of enzymes by siderophore-producing microorganisms.
  152. (2006). Feo - Transport of ferrous iron into bacteria.
  153. (2003). FeoB is not required for ferrous iron uptake in Campylobacter jejuni.
  154. (1999). Ferrioxaminemediated iron (III) utilization by Salmonella enterica.
  155. (1999). Ferritin mutants of Escherichia coli are iron deficient and growth impaired, and fur mutants are iron deficient.
  156. (1987). Ferrous iron transport mutants in Escherichia coli K-12.
  157. (2004). Free and hemophore-bound heme acquisitions through the outer membrane receptor HasR have different requirements for the TonB-ExbB-ExbD complex.
  158. (1995). Functional domains of the Escherichia coli ferric uptake regulator protein (Fur).
  159. (2005). Functional interactions between the carbon and iron utilization regulators, Crp and Fur, in Escherichia coli.
  160. (1988). Fur (ferric uptake regulation) protein and CAP (catabolite-activator protein) modulate transcription of fur gene in Escherichia coli.
  161. (1994). Fur (ferric uptake regulation) protein interaction with target DNA: Comparison of gel retardation, footprinting and electron microscopy analyses.
  162. (2000). Fur positive regulation of iron superoxide dismutase in Escherichia coli: Functional analysis of the sodB promoter.
  163. (1994). Fur regulon in Gram-negative bacteria. Identification and characterization of new iron-regulated Escherichia coli genes by a Fur titration assay.
  164. (2002). Fur-DNA interactions at the bi-directional fepDGC-entS promoter region in Escherichia coli.
  165. (2002). Fur-mediated transcriptional and post-transcriptional regulation of FeSOD expression in Escherichia coli.
  166. Generation of a superoxide dismutase (SOD)-deficient mutant of Campylobacter coli: evidence for the significance of SOD in Campylobacter survival and colonization.
  167. (1993). Genetic manipulation of Campylobacter: evaluation of natural transformation and electro-transformation.
  168. (1998). Genetic manipulation of enteric Campylobacter species.
  169. (1989). Genetic mapping of katB, a locus that affects catalase 2 levels in Bacillus subtilis.
  170. (1970). Genetic techniques in studies of bacterial metabolism.
  171. (1994). Genetic, enzymatic, and pathogenic studies of the iron superoxide dismutase of Campylobacter jejuni.
  172. (2000). Genetics and regulation of two distinct haem-uptake systems, phu and has, in Pseudomonas aeruginosa.
  173. (2001). Genome sequence of enterohaemorrhagic Escherichia coli 0157:H7.
  174. (1990). Genomic organization and expression of Campylobacter flagellin genes.
  175. (1997). Genotypic diversity of Campylobacter lari isolated from mussels and oysters in The Netherlands.
  176. (2003). Global iron-dependent gene regulation in Escherichia coli: A new mechanism for iron homeostasis.
  177. (1992). Gonococcal transferrin-binding protein 1 is required for transferrin utilization and is homologous to TonB-dependent outer membrane receptors.
  178. (1994). Gonococcal transferrinbinding protein 2 facilitates but is not essential for transferrin utilization.
  179. (1990). Growth and siderophore production by Bordetella pertussis under iron-restricted conditions.
  180. (2002). Growth stimulation of intestinal commensal Escherichia coli by catecholamines: a possible contributory factor in trauma-induced sepsis.
  181. (2001). Haem utilization in Vibrio cholerae involves multiple TonB-dependent haem receptors.
  182. (1985). Haemophilus influenzae can use human transferrin as a sole source for required iron.
  183. (2003). Haemophoremediated signal transduction across the bacterial cell envelope in Serratia marcescens: The inducer and the transported substrate are different molecules.
  184. (1988). Helicobacter pylori ribBA- mediated riboflavin production is involved in iron acquisition.
  185. (2005). Heme oxygenase and heme degradation.
  186. (2006). Heme utilization in Campylobacter jejuni.
  187. (2003). Hepcidin, a key regulator of iron metabolism and mediator of anemia of inflammation.
  188. (1988). High-voltage electroporation of bacteria: Genetic transformation of Campylobacter jejuni with plasmid DNA.
  189. (1998). Host resistance to intracellular infection: Mutation of natural resistance-associated macrophage protein 1 (Nramp1) impairs phagosomal acidification.
  190. (1996). Host signal transduction and endocytosis of Campylobacter jejuni.
  191. (1957). Human infections with Vibrio fetus and a closely related vibrio.
  192. (1984). Human serum antibody response to Campylobacter jejuni infection as measured in an enzyme-linked immunosorbent assay.
  193. (1986). Hydrogen peroxide-inducible proteins in Salmonella typhimurium overlap with heat shock and other stress proteins.
  194. (1987). Hypochlorite scavenging by Pseudomonas aeruginosa alginate.
  195. (1996). Identification and analysis of a gene encoding a Fur-like protein of Staphylococcus epidermidis.
  196. (1995). Identification and characterisation of genes encoding the human transferrin-binding proteins from Haemophilus influenzae.
  197. (1988). Identification and characterization of the human lactoferrin-binding protein from Neisseria meningitidis.
  198. (1988). Identification and characterization of the transferrin receptor from Neisseria meningitidis.
  199. (1986). Identification and characterization of two Campylobacter jejuni adhesins for cellular and mucous substrates.
  200. (1993). Identification and cloning of a Fur homologue from Neisseria gonorrhoeae.
  201. (1994). Identification and cloning of a fur homologue from Neisseria meningitidis.
  202. (1991). Identification and cloning of a fur regulatory gene in Yersinia pestis.
  203. (1998). Identification and molecular analysis of lbpAB, which encodes the two-component meningococcal lactoferrin receptor.
  204. (1989). Identification and molecular analysis of oxyR-regulated promoters important for the bacterial adaptation to oxidative stress.
  205. (1997). Identification and molecular cloning of a gene encoding a fibronectin-binding protein (CadF) from Campylobacter jejuni.
  206. (1991). Identification and purification of transferrin- and lactoferrin-binding proteins of Bordetella pertussis and Bordetella bronchiseptica.
  207. (1996). Identification methods for campylobacters, helicobacters, and related organisms.
  208. (2007). Identification of a Campylobacter jejuni protein that cross-reacts with cholera toxin.
  209. (1994). Identification of a locus involved in the utilisation of iron by Haemophilus influenzae.
  210. (1998). Identification of a zinc-specific metalloregulatory protein, Zur, controlling zinc transport operons in Bacillus subtilis.
  211. (2005). Identification of an Escherichia coli 0157:H7 heme oxygenase with tandem functional repeats.
  212. (1998). Identification of Campylobacter jejuni promoter sequences.
  213. (2004). Identification of tandem duplicate regulatory small RNAs in Pseudomonas aeruginosa involved in iron homeostasis.
  214. (1999). Identification of the enteropathogens Campylobacter jejuni and Campylobacter coli based on the cadF virulence gene and its product.
  215. (1994). Identification of the iroA gene product of Neisseria meningitidis as a lactoferrin receptor.
  216. (1989). Identification of the transferrin- and lactoferrin-binding proteins in Haemophilus influenzae.
  217. (1997). Identification, characterization and immunogenicity of the lactoferrin-binding protein from Helicobacter pylori.
  218. (2002). Impact of transport crate reuse and of catching and processing on Campylobacter and Salmonella contamination of broiler chickens.
  219. (1994). Impairment of the human phagocyte oxidative responses caused by Leishmania lipophosphoglycan (LPG): In vitro studies.
  220. (1999). In vivo adaptation of attenuated Salmonella typhimurium results in increased growth upon exposure to norepinephrine.
  221. (1997). In vivo kinetics of a redox-regulated transcriptional switch.
  222. Inactivation of Campylobacter jejuni flagellin genes by homologous recombination demonstrates that flaA but not flaB is required for invasion.
  223. (2004). Increased gut-derived norepinephrine release in sepsis: Up-regulation of intestinal tyrosine hydroxylase.
  224. (1997). Induction of Gram-negative bacterial growth by neurochemical containing banana (Musa x paradisiaca) extracts.
  225. (1998). Infection genomics: Nramp1 as a major determinant of natural resistance to intracellular infections.
  226. (1996). Infection, the gut and the development of the multiple organ dysfunction syndrome.
  227. (1981). Infective dose of Campylobacter jejuni in milk.
  228. (1986). Influence of iron on growth, morphology, outer membrane protein composition, and synthesis of siderophores in Campylobacter jejuni.
  229. (1988). Influence of strain characteristics and immunity on the epidemiology of Campylobacter infections in Thailand.
  230. (1990). Inhibition of polymorphonuclear leukocyte function by Legionella pneumophila exoproducts.
  231. (1987). Interaction of lactoferrin and transferrins with the outer membrane of Bordetella pertussis.
  232. (2002). Interactions of haemoglobin with the Neisseria meningitidis receptor H: The role of TonB and an intact proton motive force.
  233. (2000). Involvement of a plasmid in virulence of Campylobacter jejuni 81-176.
  234. (2003). Involvement of enterobactin in norepinephrine-mediated iron supply from transferrin to enterohaemorrhagic Escherichia coli.
  235. (1998). Involvement of vulnibactin and exocellular protease in utilisation of transferrin- and lactoferrin-bound iron by Vibrio vulnificus.
  236. (1992). Iron acquisition and hemolysin production by Campylobacter jejuni.
  237. (2004). Iron acquisition and regulation in Campylobacter jejuni.
  238. (2000). Iron acquisition and virulence in Helicobacter pylori: a major role for FeoB, a high-affinity ferrous iron transporter.
  239. (2002). Iron acquisition by Gram-positive bacterial pathogens.
  240. (1988). Iron acquisition by Haemophilus influenzae.
  241. (1993). Iron acquisition by Helicobacter pylori: Importance of human lactoferrin.
  242. (2003). Iron acquisition from host molecules by Campylobacter jejuni.
  243. (2005). Iron acquisition from transferrin by Candida albicans depends on the reductive pathway.
  244. (1990). Iron acquisition in Pasteurella haemolytica: expression and identification of a bovine-specific receptor.
  245. (1999). Iron acquisition systems in the pathogenic Neisseria.
  246. (1999). Iron and activated oxygen species in biology: The basic chemistry.
  247. (2002). Iron and hydrogen peroxide detoxification properties of DNAbinding protein from starved cells - A ferritin-like DNA-binding protein of Escherichia coli.
  248. (1978). Iron and infection.
  249. (2004). Iron and microbial infection.
  250. (1993). Iron and oxygen regulation of Escherichia coli MnSOD expression: Competition between the global regulators Fur and ArcA for binding to DNA.
  251. (2000). Iron metabolism in pathogenic bacteria.
  252. (2008). Iron metabolism, transport and regulation.
  253. (1994). Iron release from transferrin by pyoverdin and elastase from Pseudomonas aeruginosa.
  254. (1991). Iron represses the expression of CFA/I fimbriae of enterotoxigenic E.
  255. (1998). Iron storage in bacteria.
  256. (1994). Iron supply of Pasteurella multocida and Pasteurella haemolytica.
  257. (1995). Iron supply of staphylococci and of micrococci by α-ketoacids.
  258. (2005). Iron transport and regulation.
  259. (2002). Iron transport and signalling in Escherichia coli.
  260. (1976). Iron transport in Escherichia coli K-12: Involvement of the colicin B receptor and of a citrate-inducible protein.
  261. (2004). Iron transport systems in Neisseria meningitidis.
  262. (1972). Iron uptake in Salmonella typhimurium: Utilization of exogenous siderophores as iron carriers.
  263. (1993). Iron uptake mechanisms in pathogenic bacteria.
  264. (2004). Iron uptake via the enterobactin system.
  265. (1997). Iron-regulated excretion of α-keto acids by Salmonella typhimurium.
  266. (1998). Iron-responsive gene regulation in a Campylobacter jejuni fur mutant.
  267. (1994). Iron-responsive genetic regulation in Campylobacter jejuni: Cloning and characterization of a fur homolog.
  268. (1997). Iron-sulfur clusters: Nature's modular, multipurpose structures.
  269. (2005). Ironing out the problem: New mechanisms of iron homeostasis.
  270. (1996). Isolation and analysis of a fur mutant of Neisseria gonorrhoeae.
  271. (1963). Isolation and analysis of the deoxyribonucleic acid of Mycoplasma mycoides var. capri.
  272. (1985). Isolation of DNA from biological specimens without extraction with phenol.
  273. (1994). Isolation of motile and non-motile insertional mutants of Campylobacter jejuni: The role of motility in adherence and invasion of eukaryotic cells.
  274. (1992). Isolation of nonchemotactic mutants of Campylobacter jejuni and their colonization of the mouse intestinal tract.
  275. (1986). Isolation of superoxide dismutase mutants in Escherichia coli: Is superoxide dismutase necessary for aerobic life?
  276. (1953). Isolement d'un vibrion saprophyte du sperme du Taureau et du vagin de la vache (Vibrio bubulus).
  277. (1990). Isoprenoid quinones of Campylobacter cryaerophila,
  278. (2001). JlpA, a novel surface-exposed lipoprotein specific to Campylobacter jejuni, mediates adherence to host epithelial cells.
  279. (2006). John McFadyean and the century of the first isolation of Campylobacter species.
  280. (1993). Kinetic and antigenic characterization of altered protein synthesis by Campylobacter jejuni during cultivation with human epithelial cells.
  281. (2000). Lack of a role for iron in the Lyme disease pathogen.
  282. (1983). Lactobacillus plantarum, an organism not requiring iron.
  283. (1972). Lactoferrin and transferrin: A comparative study.
  284. (2002). Lactoferrin and transferrin: Functional variations on a common structural framework.
  285. (2004). Lactoferrin receptors in Gram-negative bacteria: Insights into the iron acquisition process.
  286. (1995). Lethal oxidative damage and mutagenesis are generated by iron in fur mutants of Escherichia coli: Protective role of superoxide dismutase.
  287. (1960). Leucocidal agents of haemolytic streptococci.
  288. (1990). Long term starvation-induced loss of antibiotic resistance in bacteria.
  289. (1992). Lysine biosynthesis in selected pathogenic fungi: Characterization of lysine auxotrophs and the cloned LYS1 gene of Candida albicans.
  290. (1992). Lysyl-tRNA synthetase gene of Campylobacter jejuni.
  291. (2005). Major structural differences and novel potential virulence mechanisms from the genomes of multiple Campylobacter species.
  292. (1989). Mechanism for iron-regulated transcription of the Escherichia coli cir gene: Metal-dependent binding of Fur protein to the promoters.
  293. (1999). Mechanisms for redox control of gene expression.
  294. (2002). Mechanisms of cellular iron acquisition: Another iron in the fire.
  295. (1989). Mechanistically novel iron (III) transport system in Serratia marcescens.
  296. (1988). Metal ion regulation of gene expression: Fur repressor-operator interaction at the promoter region of the aerobactin system of pColV-K30.
  297. (2004). Microbial endocrinology and infectious disease in the 21st century.
  298. (2008). Microbial endocrinology: How stress influences susceptibility to infection.
  299. (2002). Microbial siderophore-mediated transport.
  300. (1995). Molecular characterization of a Campylobacter jejuni lipoprotein with homology to periplasmic siderophore-binding proteins.
  301. (2000). Molecular characterization of Campylobacter jejuni virulence determinants.
  302. (1995). Molecular characterization of katA from Campylobacter jejuni and generation of a catalase-deficient mutant of Campylobacter coli by interspecific allelic exchange
  303. (1998). Molecular characterization of LbpB, the second lactoferrin-binding protein of Neisseria meningitidis.
  304. (1993). Molecular characterization of the 98-kilodalton iron-regulated outer membrane protein of Neisseria meningitidis.
  305. (1991). Molecular characterization of the soxRS genes of Escherichia coli: Two genes control a superoxide stress regulon.
  306. (2001). Molecular cloning: a laboratory manual., Third edn.
  307. (1971). Molecular weight, singlechain structure and amino acid composition of human lactoferrin.
  308. (1987). Multiple catalases in Bacillus subtilis.
  309. (1986). Multiplication of Shigella flexneri within HeLa cells: Lysis of the phagocytic vacuole and plasmid-mediated contact hemolysis.
  310. (1998). Mutation in peb1A of Campylobacter jejuni reduces interactions with epithelial cells and intestinal colonization of mice.
  311. (2006). Natural resistance, iron and infection: A challenge for clinical medicine.
  312. (1990). Natural transformation in Campylobacter species.
  313. (1997). Neuroendocrine-bacterial interactions in a neurotoxininduced model of trauma.
  314. (2003). Neuromodulation of enteropathogen internalization in Peyer's patches from porcine jejunum.
  315. (1979). Nonenteric toxins of Staphylococcus aureus.
  316. (2006). Norepinephrine increases the pathogenic potential of Campylobacter jejuni.
  317. (1997). Norepinephrine-induced expression of the K99 pilus adhesion of enterotoxigenic Escherichia coli.
  318. (2005). NssR, a member of the Crp-Fnr superfamily from Campylobacter jejuni, regulates a nitrosative stress-responsive regulon that includes both a single-domain and a truncated haemoglobin.
  319. (1992). Nucleotide sequence of Streptococcus mutans superoxide dismutase gene and isolation of insertion mutants.
  320. (1985). Nucleotide sequence of the iron regulatory gene fur.
  321. (2004). Nucleotide sequences and comparison of two large conjugative plasmids from different Campylobacter species.
  322. (1994). Observation of binding and polymerization of Fur repressor onto operator-containing DNA with electron and atomic force microscopes.
  323. (1999). Opening the iron box: Transcriptional metalloregulation by the Fur protein.
  324. (1987). Operator sequences of the aerobactin operon of plasmid ColV-K30 binding the ferric uptake regulation (fur) repressor.
  325. (1960). Ovine vibrionic abortion caused by a new variety of Vibrio.
  326. (1986). Oxygen-dependent mutagenesis in Escherichia coli lacking superoxide dismutase.
  327. (1995). Oxygen, iron, carbon, and superoxide control of the fumarase fumA and fumC genes of Escherichia coli: Role of the arcA, fnr, and soxR gene products.
  328. (1999). OxyR and SoxRS regulation of fur.
  329. (1989). OxyR, a positive regulator of hydrogen peroxide-inducible genes in Escherichia coli and Salmonella typhimurium, is homologous to a family of bacterial regulatory proteins.
  330. (2001). Pathogenesis of enteric Campylobacter infection.
  331. (1997). Pathogenesis of enteric infection by Campylobacter.
  332. (2004). Pathogenic Escherichia coli, Shigella, and Salmonella.
  333. (2000). Pathogenic Neisseriae can use hemoglobin, transferrin, and lactoferrin independently of the tonB locus.
  334. (2001). PerR controls oxidative stress resistance and iron storage proteins and is required for virulence in Staphylococcus aureus.
  335. (2000). Phase variation of a β-1,3 galactosyltransferase involved in generation of the ganglioside GM1-like lipo-oligosaccharide of Campylobacter jejuni.
  336. (1999). Physiological characterization of viable-but-nonculturable Campylobacter jejuni cells.
  337. (1994). Pleiotropic effects of a Yersinia pestis fur mutation.
  338. (2005). PorA protein of Campylobacter jejuni is not a cytotoxin mediating inflammatory diarrhoea.
  339. (1999). Porins OmpC and PhoE of Escherichia coli as specific cell-surface targets of human lactoferrin.
  340. (1985). Positive control of a regulon for defenses against oxidative stress and some heat-shock proteins in Salmonella typhimurium.
  341. (2000). Poultry infections and their control at the farm level.
  342. (1993). Preparation and analysis of isogenic mutants in the transferrin receptor protein genes, tbpA and tbpB, from Neisseria meningitidis.
  343. (1979). Preparative and analytical purification of DNA from agarose.
  344. (2005). Prevalence of Campylobacter in the food and water supply: Incidence, outbreaks, isolation and detection.
  345. (1996). Prevalence of cytolethal distending toxin production in Campylobacter jejuni and relatedness of Campylobacter sp. cdtB genes.
  346. (1977). Production of a capsule by Neisseria gonorrhoeae.
  347. (1996). Production of an autoinducer of growth by norepinephrine cultured Escherichia coli O157:H7.
  348. (1996). Production of Shiga-like toxins by Escherichia coli O157:H7 can be influenced by the neuroendocrine hormone norepinephrine.
  349. (1994). Promoter and operator determinants for Fur-mediated iron regulation in the bidirectional fepA-fes control region of the Escherichia coli enterobactin system.
  350. (1985). Promoter mapping and transcriptional regulation of the iron assimilation system of plasmid
  351. (1995). Purification and characterization of ferritin from Campylobacter jejuni.
  352. (1979). Purification and characterization of hydroperoxidase
  353. (1994). Purification of a MalE-SoxS fusion protein and identification of the control sites of Escherichia coli superoxide-inducible genes.
  354. (1979). Purification of the o-Dianisidine peroxidase from Escherichia coli B. Physicochemical characterization and analysis of its dual catalatic and peroxidatic activities.
  355. (2002). Quantification of known components of the Escherichia coli TonB energy transducing system: TonB, ExbB, ExbD and FepA.
  356. (1944). Raw hen egg white and the role of iron in growth inhibition of Shigella dysenteriae, Staphylococcus aureus, Escherichia coli, and Saccharomyces cerevisiae.
  357. (2002). Recognition of DNA by Fur: a reinterpretation of the Fur box consensus sequence.
  358. (2004). Recognition of iron-free siderophores by TonB-dependent iron transporters.
  359. (2002). Reduction of iron by extracellular iron reductases: Implications for microbial iron acquisition.
  360. (1981). Regulation of ferric iron transport in Escherichia coli K-12: Isolation of a constitutive mutant.
  361. (1997). Regulation of fumarase (fumB) gene expression in Escherichia coli in response to oxygen, iron and heme availability: Role of the arcA, fur, and hemA gene products.
  362. (2002). Regulation of inducible peroxide stress responses.
  363. (2002). Regulation of the Bacillus subtilis fur and perR genes by PerR: Not all members of the PerR regulon are peroxide-inducible.
  364. (1999). Regulation of the OxyR transcription factor by hydrogen peroxide and the cellular thiol-disulfide status.
  365. (1973). Related vibrio in stools.
  366. (1913). Report of the departmental committee appointed by the board of agriculture and fisheries to enquire into epizootic abortion, III.
  367. (1978). Repressor recognition of operators and effectors
  368. (1996). Resistance to intracellular infections: Comparative genomic analysis of NRAMP1.
  369. (2007). Riboflavin biosynthesis is associated with assimilatory ferric reduction and iron acquisition by Campylobacter jejuni.
  370. (1993). Role of Campylobacter jejuni flagella as colonization factors for three-day-old chicks: Analysis with flagellar mutants.
  371. (2000). Role of catalase in Campylobacter jejuni intracellular survival Infection and
  372. (1993). Role of flagella in adherence, internalization, and translocation of Campylobacter jejuni in nonpolarized and polarized epithelial cell cultures Infection and
  373. (1999). Role of iron in Nramp1-mediated inhibition of mycobacterial growth.
  374. (1993). Role of iron in regulation of virulence genes
  375. (2003). Role of microfilaments and microtubules in the invasion of INT407 cells by Campylobacter jejuni.
  376. (2003). Role of receptor proteins for enterobactin and 2,3-dihydroxybenzoylserine in the virulence of Salmonella enterica.
  377. (2001). Roles of metal ions and hydrogen peroxide in modulating the interaction of the Bacillus subtilis PerR peroxide regulon repressor with operator DNA.
  378. (2006). RyhB small RNA modulates the free intracellular iron pool and is essential for normal growth during iron limitation in Escherichia coli.
  379. (1990). Salmonella interactions with polarized human intestinal Caco-2 epithelial cells
  380. (1989). Scavenging by alginate of free radicals released by macrophages.
  381. (1998). Seasonal variation of thermophilic campylobacters in lambs at slaughter.
  382. (1947). Septicemie grave eu cours de la grossesse, due à un vibrion. Avortement consecutif.
  383. (1996). Sequence specificity for DNA binding by Escherichia coli SoxS and Rob proteins.
  384. (2000). Sequential spread of Campylobacter infection in a multipen broiler house.
  385. (1992). Short protocols in molecular biology., Second edn. New York: Greene Publishing Associates and
  386. (2007). Siderophore-based iron acquisition and pathogen control.
  387. (1986). Siderophore-mediated iron acquisition from transferrin by Pseudomonas aeruginosa.
  388. (1999). Site-directed disulfide bonding reveals an interaction site between energy-coupling protein TonB and BtuB, the outer membrane cobalamin transporter.
  389. (1995). Site-directed replacement of the coaxial heme ligands of bacterioferritin generates heme-free variants.
  390. (1919). Some morphological and biochemical characters of the spirilla (Vibrio fetus n. sp.) associated with disease of the fetal membranes in cattle.
  391. (1996). SoxR, a [2Fe-2S] transcription factor, is active only in its oxidized form.
  392. (1990). soxR, a locus governing a superoxide response regulon in Escherichia coli K-12.
  393. (1994). SoxS, an activator of superoxide stress genes in Escherichia coli. Purification and interaction with DNA.
  394. (1918). Spirilla associated with disease of the fetal membranes in cattle (infectious abortion).
  395. (1987). Spontaneous mutagenesis and oxidative damage to DNA in Salmonella typhimurium.
  396. (1994). Staphylococci express a receptor for human transferrin: Identification of a 42-kilodalton cell wall transferrin-binding protein.
  397. (2005). Staphylococcus aureus siderophore-mediated iron-acquisition system plays a dominant and essential role in the utilization of transferrin-bound iron.
  398. (1999). Stimulation of bacterial growth by heat-stable, norepinephrine-induced autoinducers.
  399. (2003). Stimulation of Staphylococcus epidermidis growth and biofilm formation by catecholamine inotropes.
  400. (1991). Stress and pathogenesis of infectious disease.
  401. (1990). Structural and functional analysis of two Campylobacter jejuni flagellin genes.
  402. (2002). Structural basis of gating by the outer membrane transporter FecA.
  403. (2001). Structural basis of the redox switch in the OxyR transcription factor.
  404. (1991). Structural dynamics and functional domains of the Fur protein.
  405. (2003). Structural evidence for iron-free citrate and ferric citrate binding to the TonB-dependent outer membrane transporter FecA.
  406. (1987). Structure of human lactoferrin at 3.2-Å resolution.
  407. (2002). Structure of the N-linked glycan present on multiple glycoproteins in the Gram-negative bacterium, Campylobacter jejuni.
  408. (1988). Structure, function and evolution of bacterial ferredoxins.
  409. (1992). Studies of the Nterminal half of human lactoferrin produced from the cloned cDNA demonstrate that interlobe interactions modulate iron release.
  410. (1966). Studies on lactoferrin, the iron binding protein of secretions.
  411. (1983). Studies on transformation of Escherichia coli with plasmids.
  412. (1996). Sulphation catalysed by the human cytosolic sulphotransferases - chemical defence or molecular terrorism?
  413. (1978). Superoxide-dependent production of hydroxyl radical catalyzed by iron-EDTA complex.
  414. (1997). Surface signalling: Novel transcription initiation mechanism starting from the cell surface
  415. (1998). Survival and growth of Campylobacter jejuni after artificial inoculation onto chicken skin as a function of temperature and packaging conditions
  416. (1996). Sympathetic discharge to mesenteric organs and the liver.
  417. (2000). Sympathetic input into the enteric nervous system.
  418. (1973). Taxonomic study of the genus Campylobacter Sébald and Véron and designation of the neotype strain for the type species, Campylobacter fetus (Smith and Taylor) Sébald and Véron.
  419. (2000). Taxonomy of the family Campylobacteraceae. In Campylobacter,
  420. (2005). Taxonomy, phylogeny, and methods for the identification of Campylobacter species.
  421. (1963). Teneur en bases da l'ADN et classification des vibrions.
  422. (1999). The absence of cecal colonization of chicks by a mutant of Campylobacter jejuni not expression bacterial fibronectin-binding protein.
  423. (1948). The aetiology of swine dysentery.
  424. (1992). The catecholamine response to multi-system trauma.
  425. (2007). The complete genome sequence of Campylobacter jejuni strain 81116 (NCTC11828).
  426. (1997). The complete genome sequence of the gastric pathogen Helicobacter pylori.
  427. (1994). The dps promoter is activated by OxyR during growth and by IHF and σs in stationary phase.
  428. (1962). The effect of electrolytes on the stability of deoxyribonucleate helix.
  429. (1999). The effect of intracellular iron concentration and nitrogen monoxide on Nramp2 expression and non-transferrin-bound iron uptake.
  430. (1988). The extent of surface contamination of retailed chickens with Campylobacter jejuni serogroups.
  431. (1996). The fbpABC locus of Neisseria gonorrhoeae functions in the periplasm-tocytosol transport of iron.
  432. (1993). The ferric ironbinding protein of pathogenic Neisseria spp. functions as a periplasmic transport protein in iron acquisition from human transferrin.
  433. (1999). The ferric uptake regulation (Fur) repressor is a zinc metalloprotein.
  434. (2002). The ferric uptake regulator of Pseudomonas aeruginosa has no essential cysteine residues and does not contain a structural zinc ion.
  435. (2001). The Fur repressor controls transcription of iron-activated and -repressed genes in Helicobacter pylori.
  436. (2000). The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences.
  437. (1974). The involvement of lactoferrin in the hyposideremia of acute inflammation.
  438. (2001). The iron-and temperature-regulated cjrBC genes of Shigella and enteroinvasive Escherichia coli strains code for colicin Js uptake.
  439. (2003). The iron-binding protein Dps confers hydrogen peroxide stress resistance to Campylobacter jejuni.
  440. (2001). The ironinduced ferredoxin FdxA of Campylobacter jejuni is involved in aerotolerance.
  441. (2000). The ironresponsive regulator Fur of Campylobacter jejuni is expressed from two separate promoters.
  442. (1962). The laboratory recognition of Vibrio fetus and a closely related Vibrio isolated from cases of human vibriosis.
  443. (1997). The Lactobacilli anomaly: Total iron abstinence.
  444. (2000). The mammalian neuroendocrine hormone norepinephrine supplies iron for bacterial growth in the presence of transferrin or lactoferrin.
  445. (2002). The membrane protein FeoB contains an intramolecular G protein essential for Fe (II) uptake in bacteria.
  446. (1988). The microbiology of multiple organ failure. The proximal gastrointestinal tract as an occult reservoir of pathogen.
  447. (1999). The Nramp1 protein and its role in resistance to infection and macrophage function.
  448. (2004). The plug domain of a neisserial TonB-dependent transporter retains structural integrity in the absence of its transmembrane beta-barrel.
  449. (1996). The redox state of the [2Fe-2S] clusters in SoxR protein regulates its activity as a transcription factor.
  450. (1994). The role of flagella of Campylobacter jejuni in colonization in the intestinal tract in mice and the cultured-cell infectivity.
  451. (1996). The role of Fur in the acid tolerance response of Salmonella typhimurium is physiologically and genetically separable from its role in iron acquisition.
  452. (2002). The role of iron in Campylobacter gene regulation, metabolism and oxidative stress defense.
  453. (1998). The role of sympathetic innervation of the gut in regulating mucosal immune responses.
  454. (1998). The seasonal variation of thermophilic campylobacters in beef cattle, diary cattle and calves.
  455. (1999). The staphylococcal transferrin-binding protein is a cell wall glyceraldehyde-3-phosphate dehydrogenase.
  456. (1998). The Staphylococcus aureus and Staphylococcus epidermidis transferrin-binding proteins are expressed in vivo during infection.
  457. (2000). The structure of the ferric siderophore binding protein FhuD complexed with gallichrome.
  458. (1998). The transferrin receptor expressed by gonococcal strain FA1090 is required for the experimental infection of human male volunteers.
  459. (2001). The Yersinia high-pathogenicity island: An iron-uptake island.
  460. (1998). The ZnuABC high-affinity zinc uptake system and its regulator Zur in Escherichia coli.
  461. (1983). Thermotolerant Campylobacter with no or weak catalase activity isolated from dogs.
  462. (1998). Three-dimensional structure of lactoferrin - implications for function, including comparisons with transferrin.
  463. (2005). TolC is involved in enterobactin efflux across the outer membrane of Escherichia coli.
  464. (1993). TonB protein and energy transduction between membranes.
  465. (1996). TonB-dependent iron supply in Salmonella by a-ketoacids and a-hydroxyacids.
  466. (2002). TonB-dependent receptors - structural perspectives
  467. (1988). Toxic DNA damage by hydrogen peroxide through the Fenton reaction in vivo and in vitro.
  468. (1999). Transcellular translocation of Campylobacter jejuni across human polarised epithelial monolayers.
  469. (1997). Transcription induction of the ferric citrate transport genes via the N-terminus of the FecA outer membrane protein, the Ton system and the electrochemical potential of the cytoplasmic membrane.
  470. (1988). Transcriptional and posttranscriptional regulation of manganese superoxide dismutase biosynthesis in Escherichia coli, studied with operon and protein fusions.
  471. (2006). Transcriptional and translational expression patterns associated with immobilized growth of Campylobacter jejuni.
  472. (2006). Translational repression is sufficient for gene silencing by bacterial small noncoding RNAs in the absence of mRNA destruction.
  473. (1992). Translocation of Campylobacter jejuni across human polarized epithelial cell monolayer cultures.
  474. (1998). Transmembrane signaling across the ligand-gated FhuA receptor: Crystal structures of free and ferrichrome-bound states reveal allosteric changes.
  475. (1998). Transport of intact porphyrin by HpuAB, the hemoglobin-haptoglobin utilization system of Neisseria meningitidis.
  476. transport: Crystal structure of FhuA with bound lipopolysaccharide.
  477. (2002). Trends in indigenous food borne disease and deaths,
  478. (1991). Two divergently transcribed genes, soxR and soxS, control a superoxide response regulon of Escherichia coli.
  479. (1960). Two modes of lysine synthesis among lower fungi: Evolutionary significance.
  480. (1992). Two stage induction of the soxRS (superoxide response) regulon of Escherichia coli.
  481. (1992). Two-stage control of an oxidative stress regulon: The Escherichia coli SoxR protein triggers redoxinducible expression of the soxS regulatory gene.
  482. (1949). Une affection méconnue de la grossesse l'infection placentaire a Vibrio foetus.
  483. (2006). Unique features of a highly pathogenic Campylobacter jejuni strain.
  484. (1993). Unusual microtubuledependent endocytosis mechanisms triggered by Campylobacter jejuni and Citrobacter freundii.
  485. (2005). Use of genome-wide expression profiling and mutagenesis to study the intestinal lifestyle of Campylobacter jejuni.
  486. (2008). Utilization of lactoferrin-bound and transferrin-bound iron by Campylobacter jejuni.
  487. (1991). Variations in Campylobacter jejuni flagellin, and flagellin genes, during in vivo and in vitro passage.
  488. (1986). Viable but nonculturable stage of Campylobacter jejuni and its role in survival in the natural aquatic environment.
  489. (1931). Vibrios (Vibrio jejuni, N. Sp.) associated with intestinal disorders of cows and calves
  490. (2004). Washington DC:
  491. (1986). Who discovered Campylobacter jejuni/coli? A historical review.
  492. (1998). X-ray absorption spectroscopy of a new zinc site in the Fur protein from Escherichia coli.
  493. (2002). X-ray crystallographic structures of the Escherichia coli periplasmic protein FhuD bound to hydroxamate-type siderophores and the antibiotic albomycin.
  494. (1993). α-Ketoacids are novel siderophores in the genera Proteus, Providencia and Morganella and are produced by amino acid deaminases.

To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.