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Ciprofloxacin does not inhibit mitochondrial functions but other antiboitics do

By K. Riesbeck, A. Bredberg and A. Forsgren

Abstract

At clinical concentrations, ciprofloxacin did not inhibit mitochondrial DNA replication, oxidative phosphorylation, protein synthesis, or mitochondrial mass (transmembrane potential). No difference in supercoiled forms of DNA was observed. The tetracyclines and chloramphenicol inhibited protein synthesis at clinically achievable concentrations, while rifampin, fusidic acid, and clindamycin did not

Publisher: 'American Society for Microbiology'
Year: 1990
DOI identifier: 10.1128/AAC.34.1.167
OAI identifier: oai:lup.lub.lu.se:3d189daa-ce3d-4f7e-8083-62ab1c788c3a
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