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Glomerular disease: Sugars and immune complex formation in IgA nephropathy

By Jonathan Barratt and Frank Eitner


Mesangial deposition of IgA is the principal trigger for the development of glomerulonephritis in IgA nephropathy (IgAN). Recurrence of IgA deposition in the majority of recipients of renal allografts suggests that this IgA is derived from a circulating pool of pathogenic IgA molecules

Publisher: Nature Publishing Group
Year: 2009
DOI identifier: 10.1038/nrneph.2009.165
OAI identifier:

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