Location of Repository

Key concepts in genetic epidemiology

By Paul R. Burton, Martin D. Tobin and John L. Hopper

Abstract

This paper was published as the Lancet, 2005, 366 (9489), pp. 941-951. It is available from http://www.sciencedirect.com/science/journal/01406736. Doi: 10.1016/S0140-6736(05)67322-9Metadata only entryThis article is the first in a series of seven that will provide an overview of central concepts and topical issues in modern genetic epidemiology. In this article, we provide an overall framework for investigating the role of familial factors, especially genetic determinants, in the causation of complex diseases such as diabetes. The discrete steps of the framework to be outlined integrate the biological science underlying modern genetics and the population science underpinning mainstream epidemiology. In keeping with the broad readership of The Lancet and the diverse background of today's genetic epidemiologists, we provide introductory sections to equip readers with basic concepts and vocabulary. We anticipate that, depending on their professional background and specialist knowledge, some readers will wish to skip some of this article

Publisher: Elsevier
Year: 2005
DOI identifier: 10.1016/S0140-6736(05)67322-9
OAI identifier: oai:lra.le.ac.uk:2381/7341
Journal:
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • http://hdl.handle.net/2381/734... (external link)
  • http://dx.doi.org/10.1016/S014... (external link)
  • http://www.sciencedirect.com/s... (external link)
  • Suggested articles


    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.