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A Stable, High Relaxivity, Diaqua Gadolinium Complex that Suppresses Anion and Protein Binding

By D. Messeri, M. P. Lowe, D. Parker and M. Botta


The high relaxivity of [GdaDO3A]3− (r1p = 12.3 mM−1 s−1, 20 MHz, 298 K, τm = 30 ns) in water is maintained in serum solution because the binding of protein and endogeneous anions, e.g. HCO3−/CO32− is suppressed by electrostatic repulsion

Year: 2001
DOI identifier: 10.1039/b108294a
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