10.1016/j.aca.2018.04.002).

HumanBrainCSF_LC-HRMS

Abstract

The dataset contains the XCMS processed and signal drift corrected data. Data table is reported in .txt format and contains the information (i.e. peak areas) about all detected metabolite features across analyzed samples and pooled quality control sample. Metabolite features are assigned by the couple of specific RT and accurate m/z ratio information and annotated with CAMERA for isotopes. Peaks were detected and integrated using XCMS software (parameters are specified in Materials and Methods). Metabolites abundances were corrected for signal drift effect by fitting a locally quadratic (loess) regression model to the QC values (as described in Materials and Methods below). A table of all identified metabolites derived from this dataset is available as supplementary table in the research article entitled “A global HILIC-MS approach to measure polar human cerebrospinal fluid metabolome: Exploring gender-associated variation in a cohort of elderly cognitively healthy subjects” (https://doi.org/10.1016/j.aca.2018.04.002). These data were log transformed prior to univariate statistical analysis to explore gender-associated differences

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Last time updated on 3/30/2019

This paper was published in NARCIS .

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