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Home-based exercise programmes for individuals with intermittent claudication: A protocol for an updated systematic review and meta-analysis

By Lee. Ingle, Sean. Pymer, Garry A. Tew, Joanne. Palmer, George E. Smith, Ian. Chetter and Amy E. Harwood


Background: The aim of this updated review is to consider the evidence base for the effectiveness of home-based exercise programmes (HEP) as a treatment option for improving walking distance in patients with IC.Methods: The Medline, EMBASE, CINAHL, PEDro and Cochrane CENTRAL databases will be searched for terms including “intermittent claudication”, “peripheral arterial disease”, “home-based exercise” and “home-based walking”. No date restrictions will be used but only articles in the English language will be included. Both randomised and non-randomised trials of HEP’s versus a comparator arm will be included, and a meta-analysis using only the randomised controlled trials will be attempted if the assumptions of heterogeneity are met. Data extraction will include study details, sample description, intervention description, length of follow up and outcomes measures. The primary outcome measure is objectively measured maximal walking distance or time, with secondary outcome measures including pain-free walking distance or time, changes in physical activity and quality of life. We will also provide a narrative description of the effective components of a home-based exercise intervention which can aid future recommendations. Conclusion: Overall, this proposed review and meta-analysis aims to provide a comprehensive and complete overview of the evidence base for HEP’s, which can aid clinicians in the management of their patients.PROSPERO registration number: CRD4201809124

Topics: Intermittent Claudication, Peripheral Arterial Disease, Exercise, Home-Based, Walking, Community, Centre for Health and Clinical Neuroscience
Publisher: SAGE Publications
Year: 2018
DOI identifier: 10.1177/2050312118818295
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