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Purinergic control of neutrophil activation

By F.M. Grassi

Abstract

Neutrophils constitute the first line of defense against invading pathogens, but they also are responsible for tissue destruction in pathological conditions. In a recent paper published in Science Signaling, Junger and colleagues show that adenosine 5'-triphosphate release and signaling through purinergic P2 receptors upon neutrophil activation by bacterial and inflammatory stimuli represents an important mechanism for effective neutrophil functional response and host protection

Topics: Settore BIO/13 - Biologia Applicata
Publisher: 'Oxford University Press (OUP)'
Year: 2010
DOI identifier: 10.1093/jmcb/mjq014
OAI identifier: oai:air.unimi.it:2434/153763
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