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Risk stratification in acute decompensated heart failure : the role of cardiac troponin

By C. Mueller


Cardiac troponins provide important prognostic information in patients with acute decompensated heart failure. In a large study by the ADHERE Investigators, 6.2% of 67,924 patients with acute decompensated heart failure were positive for cardiac troponin; these individuals had lower blood pressure and lower ejection fraction than those who were negative for troponin. The study revealed that in-hospital mortality was significantly higher for troponin-positive patients than for troponin-negative individuals (8.0% vs 2.7%; P>0.001). Future studies need to define which treatment changes could improve outcome in troponin-positive patients with acute decompensated heart failure

Publisher: Nature Publishing Group
Year: 2008
DOI identifier: 10.1038/ncpcardio1342
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Provided by: edoc
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