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Beyond the human genome: microbes, metaphors and what it means to be human in an interconnected post-genomic world

By Brigitte Nerlich and Iina Hellsten

Abstract

Four years after the completion of the Human Genome Project, the US National Institutes for Health launched the Human Microbiome Project on 19 December 2007. Using metaphor analysis, this article investigates reporting in English-language newspapers on advances in microbiomics from 2003 onwards, when the word “microbiome” was first used. This research was said to open up a “new frontier” and was conceived as a “second human genome project”, this time focusing on the genomes of microbes that inhabit and populate humans rather than focusing on the human genome itself. The language used by scientists and by the journalists who reported on their research employed a type of metaphorical framing that was very different from the hyperbole surrounding the decipherment of the “book of life”. Whereas during the HGP genomic successes had been mainly framed as being based on a unidirectional process of reading off information from a passive genetic or genomic entity, the language employed to discuss advances in microbiomics frames genes, genomes and life in much more active and dynamic ways

Publisher: Taylor & Francis
Year: 2009
OAI identifier: oai:eprints.nottingham.ac.uk:1305
Provided by: Nottingham ePrints

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Citations

  1. (2005). A New Literary Metaphor for the Genome or Proteome. doi
  2. (2007). A top-down systems biology view of microbiomemammalian metabolic interactions in a mouse model. Molecular Systems Biology,
  3. (2007). Available At:
  4. (2007). Available At: Http://Www.Nih.Gov/News/Pr/Dec2007/Od-19.Htm [Accessed
  5. (2007). Available At: Http://Www.Nova.Edu/Ssss/QR/QR10-2/Schmitt.Pdf [Accessed
  6. (2007). BCM Human Microbiome Projects to sequence 150 bacteria, sample Human Metagenome.
  7. (2007). Biology‟s next revolution.
  8. (2005). Communicating novel and conventional scientific metaphors: A study of the development of the metaphor of genetic code.
  9. (2003). Deciphering the human genome, In
  10. (2005). Extending our view of self: The Human Gut Microbiome Initiative (HGMI).
  11. (2004). From genes to ecosystems: The ocean‟s new frontier.
  12. (2008). Genetics and genomics: The ethics and politics of metaphorical framing In:
  13. (2004). Genomics: Shifts in metaphorical landscape between
  14. (2006). Maps, books and other metaphors for systems biology.
  15. (2004). Microbial population genomics and ecology: a new frontier.
  16. (2007). Multimodal discourse analysis of probiotic web advertising.
  17. (2007). Notes on metaphors, notes as metaphors: The genome as Musical spectacle.
  18. (2007). Press Release: NIH Launches Human Microbiome Project.
  19. (2006). Re: Systems Biology -- The Music of Life and the Theory of (Biological) Relativity. ACTA. Available At: Intentblog: Available at: Http://Www.Intentblog.Com/Archives/2006/10/Prof_Denis_Nobl.Html [Accessed
  20. (2003). Response From Jeffrey I. Gordon et al.: Commensal bacteria make a difference. Trends in
  21. (2005). Special Issue: The Genome and Its Publics: Towards a Social and Cultural Understanding of Genomics.
  22. (2005). Systematic metaphor analysis as a method of qualitative research.
  23. (2002). The Book of Life: How the human genome project was revealed to the public. Health: An interdisciplinary journal for the social study of health, illness and medicine,
  24. (2002). The human body as microbial observatory.
  25. (2007). The Human Microbiome Project. doi
  26. (2001). The meaning and impact of the human genome sequence for microbiology.
  27. (2008). The moral careers of microbes and the rise of the matrons: An analysis of UK national press coverage of methicillin resistant staphylococcus aureus (MRSA)
  28. (2006). The Music of Life (Oxford,
  29. (2003). The new genome sequence is a jazz score.
  30. (1936). The Philosophy of Rhetoric
  31. (1976). The Selfish Gene (Oxford,
  32. (2007). Understanding our Microbial Planet: The New Science of Metagenomics: http://dels.nas.edu/dels/rpt_briefs/metagenomics_final.pdf
  33. (2007). What are we? The social construction of the human biological self.
  34. (2008). What is genomics and post-genomics? Natural Environment Research Council: http://www.nerc.ac.uk/research/programmes/proteomics/background/whati s.asp
  35. (2006). Who are we? Indigenous microbes and the ecology of human diseases.
  36. (2008). Will systems biology bring probiotics to the table? The Seven Stones Blog. Available at:

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