Skip to main content
Article thumbnail
Location of Repository

Evidence of complex involvement of serotonergic genes with restrictive and binge purge subtypes of anorexia nervosa

By Kirsty Margaret Kiezebrink, Evleen T. Mann, Sarah R. Bujac, Michael J. Stubbins, David A. Campbell and John E. Blundell


Peer reviewedPreprin

Topics: Eating disorder, anorexia nervosa, genetics, serotonin, serotonin recpetor, body-mass index, acute tryptophan depletion, term weight restoration, decreases food-intake, Bulimia-Nervosa, eating disorders, 5-HT2C receptor, structured interview, association, appetite, QP Physiology, QP
Year: 2010
DOI identifier: 10.3109/15622975.2010.484550
OAI identifier:

Suggested articles


  1. (2001). 29 Fichter M,Quadflieg N.
  2. (2003). 5-HT1B receptor knockout mice show a compensatory reduction in 5-HT2C receptor function. doi
  3. (1999). 5-HT2A receptor gene polymorphisms in anorexia nervosa and bulimia nervosa. doi
  4. (1997). 5-HT2C receptor activation decreases appetite and body weight in obese subjects. doi
  5. (1998). A controlled family study of anorexia nervosa and bulimia nervosa - Psychiatric disorders in first-degree relatives and effects of proband comorbidity. doi
  6. (1983). A network Algorithm for performing Fisher's Exact Test in r x c Contingency Tables. doi
  7. (2000). A novel neurotensin peptide analog given extracranially decreses food intake and weight in rodents. doi
  8. (2005). A Review and Primer of Molecular Genetic. doi
  9. (1998). Alterations in serotonin activity and psychiatric symptoms after recovery from bulimia nervosa. doi
  10. (2001). Altered response to meta-chlorophenylpiperazine in anorexia nervosa: Support for a persistent alteration of serotonin activity after short-term weight restoration. doi
  11. (1991). Altered serotonin activity in anorexia nervosa after long-term weight restoration. Does elevated cerobrospinal fluid 5-hydroxyindoleactic acid level correlate with rigid and obsessive behaviour? Archive General Psychiatry. doi
  12. (1982). Anorexia Nervosa a Mulitidimensional perspective.
  13. (2009). Anorexia Nervosa in Identical Triplets. Cns Spectrums.
  14. (1981). Anorexia Nervosa in Twins. doi
  15. (1997). Anorexia nervosa, obsessional behaviour, and serotonin. doi
  16. (2003). Anxiolytic effects of acute tryptophan depletion in anorexia nervosa. doi
  17. (2009). Association between serotonin transporter gene polymorphism and eating disorders: A meta-analytic study doi
  18. (2003). Association of the 5-HT2c gene with susceptibility and minimum body mass index in anorexia nervosa. doi
  19. (1999). Brain mechanisms associated with depressive relapse and associated cognitive impairment following acute tryptophan depletion. doi
  20. (2003). Candidate genes for anorexia nervosa in the 1 p33-36 linkage region: serotonin 1D and delta opioid receptor loci exhibit significant association to anorexia nervosa. doi
  21. (1994). Diagnostic and statistical manual of mental disorders, fourth edition DSM-IV doi
  22. (2001). Double-blind placebo-controlled administration of fluoxetine in restricting- and restricting-purging-type anorexia nervosa. doi
  23. (1995). Eating disorder and epilepsy in mice lacking 5-HT2C serotonin receptors. doi
  24. (1990). Eating Disorders and Depression - Is There a Serotonin Connection. Biol Psychiatry. doi
  25. (2004). Eating disorders, serotonin transporter polymorphisms and potential treatment response. doi
  26. (1995). Exact tests for association between alleles at arbitrary numbers of loci. doi
  27. (2005). Gender differences in associations of eating pathology between mothers and their adolescent offspring. doi
  28. (1990). Genes and the aetiology of eating disorders. In:McGuffin doi
  29. (1999). Increased binding at 5-HT1A, 5-HT1B, and 5-HT2A receptors and 5-HT transporters in diet-induced obese rats. doi
  30. (2001). Individual-specific risk factors for anorexia nervosa: a pilot study using a discordant sister-pair design. doi
  31. (2008). Interaction between serotonin 5-HT2A receptor gene and dopamine transporter (DAT1) gene polymorphisms influences personality trait of persistence in Austrian Caucasians. doi
  32. (1977). Is There a Role for Serotonin (5-Hydroxytryptamine) in Feeding.
  33. (2003). Kipman A,Foulon C. doi
  34. (1996). Moderate dieting causes 5-HT2C receptor supersensitivity. doi
  35. (2007). Molecular genetic studies of eating disorders - Current status and future directions. doi
  36. (1995). Mortality in anorexia nervosa.
  37. (2000). Obesity: an epidemic in need of therapeutics. doi
  38. (2002). Parabrachial infusion of -fenfluramine reduces food intake: Blockade by the 5-HT1B antagonist SB-216641. doi
  39. (2006). Pharmacotherapy for obesity. doi
  40. (2001). Polymorphism of the serotonin 5-HT1B receptor gene (HTR1B) associated with minimum lifetime body mass index in women with bulimia nervosa. doi
  41. (2002). Reduced 5-HT2A receptor binding after recovery from anorexia nervosa. doi
  42. (1988). Reduction of feeding behavior by the serotonin uptake inhibitor sertraline. doi
  43. (2000). Separate systems for serotonin and leptin in appetite control. doi
  44. (2005). Serotonin alterations, in anorexia and bulimia nervosa: New insights from imaging studies. doi
  45. (1998). Serotonin and appetite regulation - Implications for the pharmacological treatment of obesity. doi
  46. (1997). Serotonin and gender-specific psychiatric disorders. doi
  47. (1997). Serotonin transporter gene-linked polymorphic region: Allele distributions in relationship to body weight and in anorexia nervosa. Life Sciences. doi
  48. (1991). Structured Interview for Anorexia and Bulimia Nervosa (SIAB). Development of a New Instrument for the Assessment of Eating Disorders. doi
  49. (1997). Sumatriptan decreases food intake and increases plasma growth hormone in healthy women. doi
  50. (1996). The 5-HT1B receptor agonist CP-94,253 reduces food intake and preserves the behavioural satiety sequence. doi
  51. (2002). The outcome of anorexia nervosa in the 20th century. doi
  52. (2004). The pharmacology of human appetite expression. doi
  53. (2006). The potential use of selective 5-HT2C agonists in treating obesity. doi
  54. (1995). Toward a unified theory of serotonin dysregulation in eating and realted disorders. doi
  55. (2007). Tryptophan as an evolutionarily conserved signal to brain serotonin: Molecular evidence and psychiatric implications. doi
  56. (2000). Tryptophan levels, excessive exercise, and nutritional status in anorexia nervosa.
  57. (1999). Twins studies and the etiology of eating disorders. doi
  58. (1979). Unique features associated with age of onset of anorexia nervosa. doi
  59. (1996). Use of Percentiles for the body mass index in Anorexia Nervosa: Diagnostic, Epidemiological and therapeutic considerations. doi

To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.