Article thumbnail
Location of Repository

Specialization of the rostral prefrontal cortex for distinct analogy processes

By E. Volle, S. J. Gilbert, R. G. Benoit and P. W. Burgess

Abstract

Analogical reasoning is central to learning and abstract thinking. It involves using a more familiar situation (source) to make inferences about a less familiar situation (target). According to the predominant cognitive models, analogical reasoning includes 1) generation of structured mental representations and 2) mapping based on structural similarities between them. This study used functional magnetic resonance imaging to specify the role of rostral prefrontal cortex (PFC) in these distinct processes. An experimental paradigm was designed that enabled differentiation between these processes, by temporal separation of the presentation of the source and the target. Within rostral PFC, a lateral subregion was activated by analogy task both during study of the source (before the source could be compared with a target) and when the target appeared. This may suggest that this subregion supports fundamental analogy processes such as generating structured representations of stimuli but is not specific to one particular processing stage. By contrast, a dorsomedial subregion of rostral PFC showed an interaction between task (analogy vs. control) and period (more activated when the target appeared). We propose that this region is involved in comparison or mapping processes. These results add to the growing evidence for functional differentiation between rostral PFC subregions

Topics: Analogy, BA 10, fMRI, reasoning, rostral prefrontal
Year: 2010
OAI identifier: oai:eprints.ucl.ac.uk.OAI2:20064
Provided by: UCL Discovery

Suggested articles

Citations

  1. (2001). A default mode of brain function.
  2. (2006). A direct comparison of anterior prefrontal cortex involvement in episodic retrieval and integration. Cereb Cortex.
  3. (2000). A neural network theory of proportional analogy-making.
  4. (1999). A system for relational reasoning in human prefrontal cortex. Psychol sci.
  5. (2006). Abstraction of mental representations: theoretical considerations and neuroscientific evidence.
  6. (2001). Analogical priming via semantic relations. Mem Cogn.
  7. (2005). Analogical reasoning and prefrontal cortex: evidence for separable retrieval and integration mechanisms. Cereb Cortex.
  8. (2001). Anterior prefrontal cortex mediates rule learning in humans. Cereb Cortex.
  9. (2004). Anterior prefrontal cortex: insights into functionfromanatomyandneuroimaging.NatRevNeurosci.5:184--194.
  10. (2007). Anterior prefrontal function and the limits of human decision-making.
  11. (2004). Attention and cognitive control as emergent properties of information representation in working memory. Cogn Affect Behav Neurosci.
  12. (2008). Brain is to thought as stomach is to?’’: investigating the role of rostrolateral prefrontal cortex in relational reasoning.
  13. (2001). Brain regions involved in prospective memory as determined by positron emission tomography.
  14. (2008). Cognitive control, hierarchy, and the rostro-caudal organization of the frontal lobes. Trends Cogn Sci.
  15. (2009). Common and dissociable prefrontal loci associated with component mechanisms of analogical reasoning. Cereb Cortex. Advance Access published on
  16. (1996). Comparison and categorization in the development of relational similarity. Child Dev.
  17. (2010). Connecting long distance: semantic distance in analogical reasoning modulates frontopolar cortex activity. Cereb Cortex.
  18. (2006). Cortical substrates for exploratory decisions in humans.
  19. (2008). Development of rostral prefrontal cortex and cognitive and behavioural disorders. Dev Med Child Neurol.
  20. Differential components of prospective memory? Evidence from fMRI.
  21. (2006). Differential functions of lateral and medial rostral prefrontal cortex (area 10) revealed by brain--behavior associations. Cereb Cortex.
  22. (2005). Dissociating the roles of right ventral lateral and dorsal lateral prefrontal cortex in generation and maintenance of hypotheses in set-shift problems. Cereb Cortex.
  23. (1999). Dorsolateral prefrontal cortex: comparative cytoarchitectonic analysis in the human and the macaque brain and corticocortical connection patterns.
  24. (1997). Educational implications of analogy. A view from case-based reasoning. Am Psychol.
  25. (2007). Efferent association pathways from the rostral prefrontal cortex in the macaque monkey.
  26. (2008). Evidence for a frontoparietal control system revealed by intrinsic functional connectivity.
  27. (1995). Forms of reasoning: insight into prefrontal functions?
  28. (1986). Frontal cortex and behavior.
  29. Frontopolar cortex mediates abstract integration in analogy. Brain Res.
  30. (2007). Function and localization within rostral prefrontal cortex (area 10). Philos Trans R Soc Lond B Biol Sci.
  31. (2002). Functional integration and inference in the brain. Prog Neurobiol.
  32. (2006). Functional specialization within rostral prefrontal cortex (area 10): a meta-analysis.
  33. (2005). Generation and recognition of abstract rules in different frontal lobe subgroups.
  34. (2000). How analogies are generated: the roles of structural and superficial similarity. Mem Cogn.
  35. (2004). How we use rules to select actions: a review of evidence from cognitive neuroscience. Cogn Affect Behav Neurosci.
  36. (2002). Human brain regions involved in visual categorization.
  37. (1997). Imaging cognitive anatomy. TrendsCogn Sci.
  38. (2005). Involvement of rostral prefrontal cortex in selection between stimulus-oriented and stimulusindependent thought.
  39. (2009). Left, but not right, rostrolateral prefrontal cortex meets a stringent test of the relational integration hypothesis.
  40. (2008). Maintaining structured information: an investigation into functions of parietal and lateral prefrontal cortices.
  41. (1995). Mental leaps. Analogy in creative thought.
  42. (2009). Mesulam’s frontal lobe mystery re-examined. Restor Neurol Neurosci.
  43. (2008). Multiple systems of category learning.
  44. (2004). Neural basis of spontaneous thought processes.
  45. (2005). Neural circuitry underlying rule use in humans and nonhuman primates.
  46. (2005). Neural correlates of intelligence as revealed by fMRI of fluid analogies.
  47. (1997). Neural substrates of fluid reasoning: an fMRI study of neocortical activation during performance of the Raven’s progressive matrices test. Cogn Psychol.
  48. (2009). Neurocognitive development of relational reasoning. Dev Sci.
  49. (2006). Performance-related activity in medial rostral prefrontal cortex (area 10) during lowdemand tasks. J Exp Psychol Hum Percept Perform.
  50. (2006). Predictive codes for forthcoming perception in the frontal cortex.
  51. (2009). Prefrontal organization of cognitive control according to levels of abstraction.
  52. (2009). Prefrontal organization of cognitive control according to levels of abstraction. Brain Res.
  53. (2008). Preparation for integration: the role of anterior prefrontal cortex in working memory.
  54. (1997). Reasoning and learning by analogy. Am Psychol.
  55. (2003). Reasoning and working memory: common and distinct neuronal processes.
  56. (2002). Recruitment of anterior dorsolateral prefrontal cortex in human reasoning: a parametric study of relational complexity. Cereb Cortex.
  57. (2009). Resting-state functional connectivity reflects structural connectivity in the default mode network. Cereb Cortex.
  58. (2005). Retrieving rules for behavior from long-term memory.
  59. (2006). Rostral prefrontal brain regions (area 10): a gateway between inner thought and the external world? In: Sebanz WPN, editor. Disorders of volition.
  60. (2001). Rostrolateral prefrontal cortex involvement in relational integration during reasoning.
  61. (2001). Searching for a baseline: functional imaging and the resting human brain. Nat Rev Neurosci.
  62. (1998). Similarity and the development of rules.
  63. (1995). Statistical parametric maps in functional imaging: a general linear approach. Hum Brain Mapp.
  64. (1997). Structure mapping in analogy and similarity. Am Psychol.
  65. (2000). Structure mapping in the comparison process.
  66. (1983). Structure-mapping: a theoretical framework for analogy. Cogn Sci.
  67. (1997). The analogical mind. Am Psychol.
  68. (2008). The brain’s default network: anatomy, function, and relevance to disease.
  69. (2005). The career of metaphor. Psychol Rev.
  70. (2000). The cognitive and neuroanatomical correlates of multitasking.
  71. (2002). The computational modeling of analogy-making. Trends Cogn Sci.
  72. (2000). The frontopolar cortex and human cognition: evidence for a rostrocaudal hierarchical organization within the human prefrontal cortex.
  73. (2005). The gateway hypothesis of rostral prefrontal cortex (area 10) function. In:
  74. (2007). The gateway hypothesis of rostral prefrontal cortex (area 10) function. Trends Cogn Sci.
  75. (2008). The microcategory account of analogy.
  76. (2002). The neural basis for category-specific knowledge: an fMRI study.
  77. (2005). The neural basis for novel semantic categorization.
  78. (2006). The neural basis of mentalizing.
  79. (2003). The neural substrate of analogical reasoning: an fMRI study. Brain Res Cogn Brain Res.
  80. (2002). The role of frontopolar cortex in subgoal processing during working memory.
  81. (1999). The role of the anterior prefrontal cortex in human cognition.
  82. (1993). The roles of similarity in transfer: separating retrievability from inferential soundness. Cogn Psychol.
  83. (2005). The rules versus similarity distinction.
  84. (2009). Transitive inference: distinct contributions of rostrolateral prefrontal cortex and the hippocampus. J Cogn Neurosci. [Epub ahead of print].
  85. (2007). Wandering minds: the default network and stimulus-independent thought.

To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.