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Nucleic acid binding properties of thyminyl and adeninyl pyrrolidine-amide oligonucleotide mimics (POM)

By T. H. Samuel Tan, David T. Hickman, Jordi Morral-Cardoner, Ian G. Beadham and Jason Micklefield

Abstract

Adeninyl POM was prepared using solid-phase peptide chemistry and shown to exhibit higher affinity for complementary DNA and RNA than the corresponding adeninyl PNA

Topics: Q1, QD
Publisher: Royal Society of Chemistry
OAI identifier: oai:eprints.hud.ac.uk:10843
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