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Synthesis of β-aminoethanesulfonyl fluorides or 2-substituted taurine sulfonyl fluorides as potential protease inhibitors

By A.J. Brouwer, T. Ceylan, T. van der Linden and R.M.J. Liskamp

Abstract

Substituted taurine sulfonyl fluorides derived from taurine or protected amino acids are conveniently synthesized from β-aminoethanesulfonyl chlorides using KF/18-crown-6 or from β-aminoethanesulfonates using DAST

Publisher: 'Elsevier BV'
Year: 2009
DOI identifier: 10.1016/j.tetlet.2009.02.130
OAI identifier: oai:eprints.gla.ac.uk:79593
Provided by: Enlighten
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