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Relation between probiotic milk administration and some bone turnover markers

By Zulema Chaila, José Ortiz Zavalla, Oscar Alarcon, Roberto Moreno, Carlos Horacio Gusils Leon, María Paola Gauffin Cano, Guillermo Oliver and Silvia Nelina Gonzalez

Abstract

The evaluation of several biochemical markers can reflect the overall skeletal rate of bone turnover. Scarce information about the effects of probiotic foods on the calcium metabolism and bone turnover markers is available. A fermented milk containing probiotic lactobacilli, as a natural strategy to prevent or slow the bone loss process in perimenospausal women, was assayed. A randomized double-blind study with apparently healthy adult women was undertaken to assess whether an improvement of markers of bone turnover levels can be achieved after oral administration of lactobacilli. The results obtained from urinary Deoxypyridinoline levels on day 0 and day 35 indicated significant differences (p0.05) between day 0 and day 35. The results obtained from two bone formation markers, serum osteocalcin and bone-specific alkaline phosphatase did not show significant differences (p>0.05). The results obtained in the present work could infer that the fermented milk consumption decreased the calcium loss in adult women.Fil: Chaila, Zulema. Fundación ALAC; ArgentinaFil: Ortiz Zavalla, José. Centro Médico Humberto 1°; ArgentinaFil: Alarcon, Oscar. Centro Médico Humberto 1°; ArgentinaFil: Moreno, Roberto. Centro Médico Humberto 1°; ArgentinaFil: Gusils Leon, Carlos Horacio. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Gauffin Cano, María Paola. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; ArgentinaFil: Oliver, Guillermo. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; ArgentinaFil: Gonzalez, Silvia Nelina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; Argentina. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia; Argentin

Topics: PROBIOTIC LACYTOBACILLI, BONE TURNOVER, PERIMENOPAUSAL WOMEN, Otras Ciencias Biológicas, Ciencias Biológicas, CIENCIAS NATURALES Y EXACTAS
Publisher: Medwell Publishing
Year: 2005
OAI identifier: oai:ri.conicet.gov.ar:11336/56499
Provided by: CONICET Digital
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