Human T Cells Specific for Autologous Non-Small Cell Lung Carcinoma

Abstract

T cells (CTLs) specific for autologous tumors is crucial both for basic and translational aspects of tumor immunology. We investigated strategies to generate CTLs specific for autologous Non-Small Cell Lung Carcinoma (NSCLC), the most frequent tumor in mankind, using circulating lymphocytes. T cell lines stably expressed the grafted chimeric TCR and specifically recognized the original NSCLC. T cells specific for NSCLC starting from autologous peripheral blood lymphocytes

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Public Library of Science (PLOS)

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Last time updated on 9/18/2018

This paper was published in Public Library of Science (PLOS).

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