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CADM1 expression is upregulated in KSHV-infected cells.

By Richard Hunte (702842), Patricia Alonso (280134), Remy Thomas (702843), Cassandra Alexandria Bazile (5146049), Juan Carlos Ramos (702846), Louise van der Weyden (119180), Juan Dominguez-Bendala (5146046), Wasif Noor Khan (5146052) and Noula Shembade (702847)

Abstract

<p>(A-B) Quantitative real-time PCR (qRT-PCR) analysis of CADM1 from HeLa and primary human B cells with and without KSHV infection. (C-D) qRT-PCR analysis of CADM1 from KSHV-associated PEL cell lines (BC-1, BC-3, BCBL-1, and UM-PEL-3) (error bars, s.e.m. of triplicate samples). (E-G) Western blot analysis of CADM1 and LANA in KSHV-infected HeLa, human primary B cells, and PEL cell lines (BC-1, BC-3, BCBL-1, and UM-PEL-3).</p

Topics: Biochemistry, Microbiology, Cell Biology, Immunology, Cancer, Mental Health, Hematology, Infectious Diseases, Virology, KSHV life cycle, survival, KSHV-infected cells, Cell Adhesion Molecule 1, PDZ binding motif, CADM 1, KSHV-encoded vGPCR-and vFLIP-mediated, CADM 1 interaction, oncogenic viruses, PBMC, NF, IKK, Membrane lipid raft, KSHV-associated PEL cells, MCD, role, activation
Year: 2018
DOI identifier: 10.1371/journal.ppat.1006968.g001
OAI identifier: oai:figshare.com:article/6189728
Provided by: FigShare
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