CADM1 expression is upregulated in KSHV-infected cells.
<p>(A-B) Quantitative real-time PCR (qRT-PCR) analysis of CADM1 from HeLa and primary human B cells with and without KSHV infection. (C-D) qRT-PCR analysis of CADM1 from KSHV-associated PEL cell lines (BC-1, BC-3, BCBL-1, and UM-PEL-3) (error bars, s.e.m. of triplicate samples). (E-G) Western blot analysis of CADM1 and LANA in KSHV-infected HeLa, human primary B cells, and PEL cell lines (BC-1, BC-3, BCBL-1, and UM-PEL-3).</p
Biochemistry, Microbiology, Cell Biology, Immunology, Cancer, Mental Health, Hematology, Infectious Diseases, Virology, KSHV life cycle, survival, KSHV-infected cells, Cell Adhesion Molecule 1, PDZ binding motif, CADM 1, KSHV-encoded vGPCR-and vFLIP-mediated, CADM 1 interaction, oncogenic viruses, PBMC, NF, IKK, Membrane lipid raft, KSHV-associated PEL cells, MCD, role, activation
DOI identifier: 10.1371/journal.ppat.1006968.g001
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