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Cell volume control in the Plasmodium -infected erythrocyte

By Richard Allen and Kiaran Kirk

Abstract

As the malaria parasite grows within the host erythrocyte, it ingests and digests far more haemoglobin than is required to provide amino acids for protein synthesis. A recent paper focuses attention on the role of this process in limiting the extent of swelling undergone by the infected cell and thereby preventing the host erythrocyte from lysing before the new generation of parasites are ready to make their escape

Topics: Keywords: adenosine triphosphatase (potassium sodium); hemoglobin; potassium; potassium channel; sodium; cell membrane; cell swelling; cell vacuole; cytolysis; cytosol; endocytosis; erythrocyte membrane; erythrocyte volume; hemolysis; hyperpolarization; ion permeab
Publisher: Elsevier
Year: 2015
DOI identifier: 10.1016/j.pt.2003.10.015
OAI identifier: oai:openresearch-repository.anu.edu.au:1885/77983
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