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钙网蛋白抑制实验性自身免疫性脑脊髓炎的发生

By 邱翔

Abstract

研究背景:活化T细胞皮下免疫能够抑制实验性自身免疫性脑脊髓炎(experimental autoimmune encephalomyelitis,EAE)的发生,而静息T细胞不能。钙网蛋白(calreticulin,CRT)是内质网Ca~(2+)结合蛋白,主要位于胞内,但有研究发现钙网蛋白能出现于活化T细胞表面。

Topics: 钙网蛋白, 小鼠脾细胞, 百日咳毒素, 尾静脉, 双抗体夹心法, 油包水, 推拉, 上清, 特异性, autoimmune
Year: 2008
OAI identifier: oai:localhost:20.500.11897/166277
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