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Extracellular RNAs: development as biomarkers of human disease

By Joseph F. Quinn, Tushar Patel, David Wong, Saumya Das, Jane E. Freedman, Louise C. Laurent, Bob S. Carter, Fred Hochberg, Kendall Van Keuren-Jensen, Matt Huentelman, Robert Spetzler, M. Yashar S. Kalani, Jorge Arango, P. David Adelson, Howard L. Weiner, Roopali Gandhi, Beatrice Goilav, Chaim Putterman and Julie A. Saugstad

Abstract

Ten ongoing studies designed to test the possibility that extracellular RNAs may serve as biomarkers in human disease are described. These studies, funded by the NIH Common Fund Extracellular RNA Communication Program, examine diverse extracellular body fluids, including plasma, serum, urine and cerebrospinal fluid. The disorders studied include hepatic and gastric cancer, cardiovascular disease, chronic kidney disease, neurodegenerative disease, brain tumours, intracranial haemorrhage, multiple sclerosis and placental disorders. Progress to date and the plans for future studies are outlined

Topics: ERCC, exRNA, extracellular RNA, biomarkers
Publisher: 'Co-Action Publishing'
Year: 2015
DOI identifier: 10.3402/jev.v4.27495.
OAI identifier: oai:dash.harvard.edu:1/22856945
Journal:

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