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Three Patients with Full Facial Transplantation

By Bohdan Pomahac, Julian Joseph Pribaz, Elof Eriksson, Ericka Bueno, J. Rodrigo Diaz-Siso, Frank John Rybicki, Donald James Annino, Dennis Paul Orgill, Edward J Caterson, Stephanie A. Caterson, Matthew Jonathan Carty, Yoon Sun Chun, Christian Edward Sampson, Jeffrey E. Janis, Daniel S. Alam, Arturo Saavedra, Joseph A. Molnar, Thomas Edrich, Francisco Miguel Marty and Stefan Gunther Tullius

Abstract

Unlike conventional reconstruction, facial transplantation seeks to correct severe deformities in a single operation. We report on three patients who received full-face transplants at our institution in 2011 in operations that aimed for functional restoration by coaptation of all main available motor and sensory nerves. We enumerate the technical challenges and postoperative complications and their management, including single episodes of acute rejection in two patients. At 6 months of follow-up, all facial allografts were surviving, facial appearance and function were improved, and glucocorticoids were successfully withdrawn in all patients

Publisher: 'Massachusetts Medical Society'
Year: 2017
DOI identifier: 10.1056/nejmoa1111432.
OAI identifier: oai:dash.harvard.edu:1/32659617
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