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Metabolic pathways possibly responsible for the differences observed in NOD and B6 mice.

By Rasmus Madsen (171679), Viqar Showkat Banday (171681), Thomas Moritz (54137), Johan Trygg (83229) and Kristina Lejon (171684)

Abstract

<p>Metabolite concentrations at weeks 0, 3, 4, 5 and 15 are indicated with colors. Red indicates significantly increased in NOD, blue indicates significantly increased in B6 and white indicates no significant difference. Enzymes involved in metabolism are also show in the plot. Red text indicates that the gene is in <i>Idd</i> region and bold, italic text indicates SNPs differentiating NOD and B6 mice. A. Metabolism around the TCA cycle with glutamic acid and glutamine. B. Metabolism of nucleic acid compounds.</p

Topics: Biochemistry, Genetics, Chemistry, Immunology, pathways, differences, observed, b6
Year: 2012
DOI identifier: 10.1371/journal.pone.0035445.g004
OAI identifier: oai:figshare.com:article/324589
Provided by: FigShare
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