Gene copy numbers for major bacterial groups per gram of cecal contents of sham-treated rats (Cont.) and glutamine-treated rats (Gln) prior to the first cycle of chemotherapy (day 0), and 6 h after the third cycle of chemotherapy (day 3), and at day 7.
<p>CPT-11 injections were carried out on day 1, 2, and 3 of the experiment (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0039764#pone-0039764-g001" target="_blank">Figure 1A</a>). Glutamine bolus was administered 30 min before each CPT-11 dose. Shown are gene copy numbers of total bacteria, <i>Bacteroides</i> group (<i>Bacteroid.</i>), <i>Lactobacillus</i> group (<i>Lactobact.</i>), <i>Bifidobacterium</i> species (<i>Bifidobact.</i>) the <i>Clostridium</i> clusters IV, XI, and XIV, and Enterobacteriaceae. Data are shown as mean of six animals (pooled standard error of the mean). Values in the same column that do not share a common superscript differ significantly (P≤0.05).</p
Microbiology, Chemistry, Cancer, numbers, bacterial, groups, gram, cecal, contents, sham-treated, rats, glutamine-treated, chemotherapy
DOI identifier: 10.1371/journal.pone.0039764.t001
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