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Immunohistochemical and Western blot analyses of TDP-43, ubiquitin, and LC3I/II expression in VCP<sup>R155H/R155H</sup> and WT brains.

By Angèle Nalbandian (131106), Katrina J. Llewellyn (131108), Masashi Kitazawa (131112), Hong Z. Yin (131114), Mallikarjun Badadani (131116), Negar Khanlou (131117), Robert Edwards (1230), Christopher Nguyen (131119), Jogeshwar Mukherjee (131122), Tahseen Mozaffar (131124), Giles Watts (131125), John Weiss (131128) and Virginia E. Kimonis (131129)

Abstract

<p>TDP-43 expression levels in (A–C) WT and (D–F) VCP<sup>R155H/R155H</sup> animals. Ubiquitin expression levels in (G–I) WT and (J–L) VCP<sup>R155H/R155H</sup> animals. LC3I/II expression levels in (M–O) WT and (P–R) VCP<sup>R155H/R155H</sup> animals. (S) Western blot analyses of TDP-43, ubiquitin and LC3I/II in brains of WT and VCP<sup>R155H/R155H</sup> animals. Alpha tubulin, β actin, and GAPDH were used as loading controls.</p

Topics: Genetics, Neuroscience, blot, analyses, wt
Year: 2012
DOI identifier: 10.1371/journal.pone.0046308.g004
OAI identifier: oai:figshare.com:article/237930
Provided by: FigShare
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