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Density fraction neutralization of WT viruses by patient IgG, anti-SR-BI, anti-CD81, anti-LDL and anti-HDL.

By George Koutsoudakis (106975), Jakub Dragun (108321), Sofia Pérez-del-Pulgar (5648806), Mairene Coto-Llerena (108326), Laura Mensa (108331), Gonzalo Crespo (106982), Patricia González (106980), Miquel Navasa (106984) and Xavier Forns (106986)

Abstract

<p>WT viruses were resolved using an iodixanol step gradient. (A) Infections of individual fractions in the presence of patient IgG, anti-SR-BI (C167) or anti-CD81 (JS-81). (B) Similar infections as described in (A) were performed with pre-incubated viruses with anti-ApoE, anti-HDL or anti-LDL. All points represent the mean of duplicate infections measured in duplicate (n = 4, ± SD). <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0052651#s3" target="_blank">Results</a> are drawn from a representative experiment of two independent experiments.</p

Topics: Chemistry, Immunology, Infectious Diseases, neutralization, wt, viruses, anti-ldl
Year: 2012
DOI identifier: 10.1371/journal.pone.0052651.g008
OAI identifier: oai:figshare.com:article/189145
Provided by: FigShare
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