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Effect of purpurin on <i>Candida albicans</i> biofilms.

By Paul Wai-Kei Tsang (296474), H. M. H. N. Bandara (296477) and Wing-Ping Fong (296479)


<p>A) Biofilm formation of <i>C</i>. <i>albicans</i> SC5314 was examined in YNB medium containing the indicated concentrations of purpurin for 24 h at 37°C. B) Purpurin was added to pre-formed (mature) <i>C</i>. <i>albicans</i> biofilms and incubated in YNB medium for an additional 24 h at 37°C. The metabolic activity of the biofilms was assessed quantitatively using XTT reduction assay. The activity of samples without purpurin treatment (i.e. DMSO only) (0 µg/ml) was taken as 100%. Results shown were the average of three independent experiments ± SD. *<i>p</i><0.01 when compared with the untreated controls.</p

Topics: Microbiology, Cell Biology, Molecular Biology, purpurin
Year: 2013
DOI identifier: 10.1371/journal.pone.0050866.g001
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Provided by: FigShare
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