Effect of purpurin on <i>Candida albicans</i> biofilms.

Abstract

<p>A) Biofilm formation of <i>C</i>. <i>albicans</i> SC5314 was examined in YNB medium containing the indicated concentrations of purpurin for 24 h at 37°C. B) Purpurin was added to pre-formed (mature) <i>C</i>. <i>albicans</i> biofilms and incubated in YNB medium for an additional 24 h at 37°C. The metabolic activity of the biofilms was assessed quantitatively using XTT reduction assay. The activity of samples without purpurin treatment (i.e. DMSO only) (0 µg/ml) was taken as 100%. Results shown were the average of three independent experiments ± SD. *<i>p</i><0.01 when compared with the untreated controls.</p

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