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Effects of NaSal on membrane input resistance (<i>R</i><sub>in</sub>) and resting membrane potential (<i>V</i><sub>rest</sub>) of neurons in the medial geniculate body (MGB).

By Yan-Yan Su (303440), Bin Luo (303443), Yan Jin (143500), Shu-Hui Wu (303446), Edward Lobarinas (303449), Richard J. Salvi (303453) and Lin Chen (54305)

Abstract

<p>(A) A series of hyperpolarizing current ranging from −30 to −80 pA (−10 pA/step) was injected into a MGB neuron for 500 ms before (Baseline), during (NaSal), and after (Wash) application of 1.4 mM NaSal. The <i>V</i><sub>rest</sub> is indicated beside the traces. (B) Mean <i>R</i><sub>in</sub> (<i>n</i> = 23) and (C) <i>V</i><sub>rest</sub> (<i>n</i> = 28) before (Baseline), during (NaSal), and after (Wash) application of 1.4 mM NaSal in the MGB neuron. Data are the mean ± SEM. ***<i>P</i><0.001 relative to baseline (one-way ANOVA with Bonferroni correction, 3 pairwise comparisons).</p

Topics: Cell Biology, Neuroscience, Physiology, nasal, membrane, resting, neurons, medial, geniculate
Year: 2013
DOI identifier: 10.1371/journal.pone.0046969.g002
OAI identifier: oai:figshare.com:article/231171
Provided by: FigShare
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