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Histophotomicrographs of slides stained with OPN antibodies using immunohistochemistry.

By Dan Wang (34472), James R. Gilbert (303420), James J. Cray Jr. (303421), Adam A. Kubala (303423), Melissa A. Shaw (303425), Timothy R. Billiar (91972) and Gregory M. Cooper (219917)


<p>OPN staining intensity were more pronounced in TLR4-/- mice than in WT mice on postoperative days 4 and 7. Typical large, rounded osteoblasts were recognized on the surface of the newly-formed bone in both groups on day 14. On day 28, less OPN positive staining was detected in both WT and TLR4<sup>−/−</sup> mice. (scale bar: 100 µm; bolded black arrows: defect margin; LB: lamellar bone; WB: woven bone; OPN(+): OPN positive stains; OB: osteoblasts).</p

Topics: Medicine, Physiology, Immunology, slides, stained, opn, antibodies
Year: 2013
DOI identifier: 10.1371/journal.pone.0046945.g002
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Provided by: FigShare
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