Comparison of antibody responses against peptides with adjuvant vs. LCP-peptides alone.

Abstract

<p>(a) LCP-2 (A₂₉₁Y-GCN4-LCP) is more immunogenic than peptide 2 (A₂₉₁Y-GCN4 without LCP) formulated with Freund’s adjuvants. Antibody responses are depicted as OD values at a serum dilution of 1∶100 where each serum was used to probe its cognate immunogen peptide or LCP. (b) Higher antibody titres were observed in mice immunised with 60 µg of <b>LCP-2</b> without Freund’s adjuvants (experiment 2). Total IgG binding to plated <b>LCP-2</b> from individual mice on day 42 serial dilution from 1∶100 to 1∶10000. Each symbol represents a single animal.</p