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Flt3L/Rapa therapy favors anergic induction in alloreactive T cells.

By Ali Xiong (304570), Lihua Duan (304571), Jie Chen (5892), Zhigang Fan (165112), Fang Zheng (54278), Zheng Tan (31226), Feili Gong (252106) and Min Fang (54205)

Abstract

<p>(A) Splenic T cells originated from cardiac allograft recipient mice at the time of rejection or at study endpoint (POD 100) were used as responder cells for MLR assay with donor-derived DCs (DC: T ratio of 1∶5). Bar graph was the summary of proliferation index (PI) of T cells isolated from different recipients. (B) The culture supernatants were harvested and cytokine IL-10 levels were quantification by ELISA. The data shown are representative of three independent experiments (*<i>P</i><0.05).</p

Topics: Immunology, favors, anergic, induction, alloreactive
Year: 2013
DOI identifier: 10.1371/journal.pone.0046230.g004
OAI identifier: oai:figshare.com:article/236072
Provided by: FigShare
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