NKT cell hypo-function in SIV-infected macaques.

Abstract

<p>Amounts of IFN-γ, IL-2, IL-13, IL-10, IL-6, and TGF-β production in culture supernatants collected 24 h following <i>in vitro</i> stimulation of PBMC from SIV-negative and SIV-infected SM, RM and CM with (A) CD1d/αGC and (B) PMA/Ca ionomycin. Open bars denote mean values of cytokines secreted from SIV-negative animals (n = ≥6) and filled bars denote mean values of SIV-infected animals (n = ≥4) from each species. Error bars denote SEM. * <i>P</i><0.05, ** <i>P</i><0.01 Mann-Whitney U test.</p

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