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NKT cell hypo-function in SIV-infected macaques.

By Namita Rout (306623), Justin Greene (306625), Simon Yue (306626), David O'Connor (306627), R. Paul Johnson (140187), James G. Else (213137), Mark A. Exley (246723) and Amitinder Kaur (228367)

Abstract

<p>Amounts of IFN-γ, IL-2, IL-13, IL-10, IL-6, and TGF-β production in culture supernatants collected 24 h following <i>in vitro</i> stimulation of PBMC from SIV-negative and SIV-infected SM, RM and CM with (A) CD1d/αGC and (B) PMA/Ca ionomycin. Open bars denote mean values of cytokines secreted from SIV-negative animals (n = ≥6) and filled bars denote mean values of SIV-infected animals (n = ≥4) from each species. Error bars denote SEM. * <i>P</i><0.05, ** <i>P</i><0.01 Mann-Whitney U test.</p

Topics: Microbiology, Immunology, Infectious Diseases, hypo-function, siv-infected
Year: 2013
DOI identifier: 10.1371/journal.ppat.1002928.g005
OAI identifier: oai:figshare.com:article/244138
Provided by: FigShare
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