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Effects of 2-amino-4-phosphonobutyrat (40–80 µM APB) on neuronal activity of single units.

By Katharina Spoida (308667), Claudia Distler (308668), Anne-Kathrin Trampe (308669) and Klaus-Peter Hoffmann (252667)


<p>Responses of 3 units (mean and standard deviation of 10 measurements) to flashed and moving ON (A) and OFF (B) visual stimuli before (control) and after intravitreous drug injection (APB; intravitreous concentration 40–80 µM). Ordinate: neuronal activity in spikes per second, abscissa: experimental conditions. APB blocks responses to all ON stimuli but spares the OFF flash response and the responses to the moving dark edge, albeit moderately decreased. Grey boxes: flash responses; black boxes: responses to moving edges in preferred direction; white boxes: responses in non-preferred direction.</p

Topics: Neuroscience, 2-amino-4-phosphonobutyrat, neuronal
Year: 2013
DOI identifier: 10.1371/journal.pone.0044724.g004
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Provided by: FigShare
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