<p>Concentration-dependence of the effect of BaCl<sub>2</sub> to reduce AP amplitude, V<sub>max</sub> and MDP in two population of beating clusters (BC). 100 µM BaCl<sub>2</sub> induced no changes in MDP in 13 out of 22 BC suggesting a small contribution or lack of I<sub>K1</sub> (<b>A, </b><b>C and E</b>), but led to membrane depolarization in 9 out of 22 BC (<b>B, D and F</b>). At concentrations at which BaCl<sub>2</sub> also blocks I<sub>Kr</sub> (500 µM), AP amplitude and V<sub>max</sub> decreased in both groups of BC. a: p<0.05 vs. Control; c: p<0.001 vs. Control.</p
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