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Lung inflammation during endotoxemia.

By Adrián González-López (317607), Alina Aguirre (317610), Inés López-Alonso (317613), Laura Amado (317617), Aurora Astudillo (317619), María Soledad Fernández-García (317622), María F. Suárez (317625), Estefanía Batalla-Solís (317627), Enrique Colado (317629) and Guillermo M. Albaiceta (317631)

Abstract

<p>N = 7/group. LPS injection increases histological damage (A-B) and neutrophilic infiltration (C-E). Mice lacking MMP-8 show a more severe injury with increased neutrophils within the lung tissue (C-D) and bronchalveolar lavage fluid (N = 4/group, E). However, there were no differences in survival (F, n = 9 per genotype, log rank test p = 0.52). *p<0.05 in post-hoc tests.</p

Topics: Biochemistry, Medicine, Immunology, inflammation
Year: 2013
DOI identifier: 10.1371/journal.pone.0039940.g001
OAI identifier: oai:figshare.com:article/286167
Provided by: FigShare
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