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Box plots presenting tumor infiltrating CD8<sup>+</sup> and Foxp3<sup>+</sup> cells for different groups of TSCC.

By Anders Näsman (167962), Mircea Romanitan (167969), Cecilia Nordfors (167959), Nathalie Grün (319685), Hemming Johansson (319686), Lalle Hammarstedt (319688), Linda Marklund (319689), Eva Munck-Wikland (319690), Tina Dalianis (167974) and Torbjörn Ramqvist (167977)

Abstract

<p> A) number of CD8<sup>+</sup> TILs, B) number Foxp3<sup>+</sup> TILs and C) the CD8<sup>+</sup>/Foxp3<sup>+</sup> cell ratio. “Good” and “poor” denotes clinical outcome. In addition to the four TSCC groups defined in the Methods section, different combinations of groups have also been compared. Thus, “HPV<sup>+</sup> good” corresponds to group A; “HPV<sup>+</sup> poor” to group B; “HPV<sup>−</sup> good” to group C; “HPV<sup>−</sup> poor” to group D; HPV<sup>+</sup> to groups A+B, HPV<sup>−</sup> to groups C+D; “good” to groups A+C; and “poor” to groups B+D. In order to better visualize the details in the lower part of <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0038711#pone-0038711-g001" target="_blank">Figure 1C</a> the upper part of the diagram including the upper whisker (at a ratio of 80) was omitted.</p

Topics: Cell Biology, Immunology, Cancer, Infectious Diseases, plots, presenting, infiltrating, cells, groups
Year: 2013
DOI identifier: 10.1371/journal.pone.0038711.g002
OAI identifier: oai:figshare.com:article/295776
Provided by: FigShare
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