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Complex force-distance curves with multiple rupture peaks detected with WT alpha-synuclein (A, B) and A30P mutant (C, D).

By Alexey V. Krasnoslobodtsev (321480), Jie Peng (188267), Josephat M. Asiago (321481), Jagadish Hindupur (321482), Jean-Christophe Rochet (321483) and Yuri L. Lyubchenko (232036)

Abstract

<p>Red, green and blue lines on the graphs are calculated WLC curves using maxima of Gaussians determined from contour length distributions corresponding to 26, 36 and 47 nm (WT) and 22, 34 and 49 nm (A30P). E) Pie charts showing relative contribution of multiple rupture events to total rupture events: 31% (WT) and 15% (A30P).</p

Topics: Biophysics, Biochemistry, Physics, Neuroscience, Chemistry, force-distance, curves, rupture, peaks, wt, alpha-synuclein, a30p, mutant
Year: 2013
DOI identifier: 10.1371/journal.pone.0038099.g005
OAI identifier: oai:figshare.com:article/303184
Provided by: FigShare
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