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Ca<sup>2+</sup> increases in acinar cells of both strains at a higher concentration of cholecystokinin.

By Sho Ogata (322706), Takashi Miki (30962), Susumu Seino (209051), Seiichi Tamai (322708), Haruo Kasai (322711) and Tomomi Nemoto (322714)


<p><i>A, C</i>. Cross-sectional fluorescence images of wild-type (WT; A) and knockout (KO; C) acini loaded with fura-2 FF-AM. <i>B.</i> Time course of changes in [Ca<sup>2+</sup>]<sub>i</sub> in apical (red box in A) and basal (blue box in A) regions of a WT acinar cell during application of 1 nM cholecystokinin (CCK). <i>D.</i> Time course of changes in [Ca<sup>2+</sup>]<sub>i</sub> in apical (red box in C) and basal (blue box in C) regions of a KO acinar cell during application of the same concentration of CCK as in B.</p

Topics: Cell Biology, Molecular Biology, Physiology, Chemistry, increases, acinar, cells, strains, higher
Year: 2013
DOI identifier: 10.1371/journal.pone.0037048.g006
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Provided by: FigShare
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