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The binding site of PLP on DndA.

By Fukun Chen (323964), Zhenyi Zhang (209572), Kui Lin (16645), Tianle Qian (323966), Yan Zhang (8098), Delin You (323967), Xinyi He (31219), Zhijun Wang (31218), Jingdan Liang (31217), Zixin Deng (31222) and Geng Wu (105382)


<p>(<b>A</b>) <b>PLP is located in a deep surface pocket on DndA.</b> The two protomers of DndA are shown in surface representation, with only one PLP shown in stick representation. The protomer of DndA harboring this PLP is colored in light grey, whereas the other protomer is colored in dark grey. Blue, red, yellow, and orange represent nitrogen, oxygen, carbon, and phosphorus atoms, respectively. (<b>B</b>) <b>The interaction interface between PLP and DndA.</b> DndA is shown in grey, with carbon atoms of its side chains and PLP shown in green. Blue, red, and orange represent nitrogen, oxygen, and phosphorus atoms, respectively. Hydrogen bonds are represented by magenta dashed lines. The orange circle indicates the presumable location of the carboxylate group of the L-cysteine substrate.</p

Topics: Biophysics, Biochemistry, Physics, Microbiology, Biological Sciences, binding, plp
Year: 2013
DOI identifier: 10.1371/journal.pone.0036635.g003
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Provided by: FigShare
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