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TUNEL and H&E stained images of untreated, HerDox-treated, and Dox-treated tumors: (A) TUNEL images of untreated tumors (left), HerDox-treated tumors (middle) (injection drug dosage: 0.004 mg/kg×6 injections), Dox-treated tumors (right) (injection drug dosage: 0.04 mg/kg×6 injections) were acquired using confocal imaging (ex: 488 nm, em: 510–560 nm, and 10×) of tumor specimens.

By Jae Youn Hwang (327533), Jinhyoung Park (327535), Bong Jin Kang (327536), David J. Lubow (327537), David Chu (327539), Daniel L. Farkas (327541), K. Kirk Shung (327542) and Lali K. Medina-Kauwe (327544)

Abstract

<p>The arrows indicate the boundary between apoptotic and normal cells. Insets represent magnified images. (B) Average fluorescence of the TUNEL images of untreated, Dox-treated, HerDox-treated tumor sections (*: p<0.01) (C) H&E images of untreated (left), HerGa-treated tumors (middle), and Dox-treated tumors (right) were obtained using the Olympus microscope incorporating a CCD camera with a RGB filter (10×). The scale bar represents 200 µm. Arrows indicate nuclear shrinkage and fragmentation.</p

Topics: Cell Biology, Biotechnology, Cancer, stained, images, dox-treated, tunel, untreated, tumors, herdox-treated, acquired, confocal, imaging, 488
Year: 2013
DOI identifier: 10.1371/journal.pone.0034463.g004
OAI identifier: oai:figshare.com:article/329753
Provided by: FigShare
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