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Effect of RGS5 deficiency on body weight, fat mass and adipocyte size.

By Wei Deng (17330), Xinan Wang (335070), Jinfeng Xiao (323340), Kuoju Chen (335071), Heng Zhou (287510), Difei Shen (335072), Hongliang Li (122229) and Qizhu Tang (283283)

Abstract

<p><b>A</b> Representative photograph of WT and KO mice fed an NC and HF for 24 weeks. <b>B</b> Growth curves of WT (black) and KO (blank) mice fed an NC (triangle) and an HF (rhombus) (n = 8–11). <b>C</b> Histology of visceral adipose tissue with hematoxylin-eosin. <b>D</b> Mean adipocyte size of the visceral adipose tissue in WT (black) and KO (blank) mice fed an NC and an HF for 24 weeks (n = 5). <b>E</b> Expression levels of mRNA related to adipogenesis in the visceral fat of WT (a dotted line at value 1) and KO (black) mice fed an HF for 24 weeks (n = 6). Values represent means ± SEM. #<i>p</i><0.05 and ##<i>p</i><0.01 compared with WT mice fed an NC; *<i>p</i><0.05 and **<i>p</i><0.01 compared with WT mice fed an HF.</p

Topics: Genetics, Chemistry, Immunology, rgs5, deficiency, adipocyte
Year: 2013
DOI identifier: 10.1371/journal.pone.0030256.g001
OAI identifier: oai:figshare.com:article/361796
Provided by: FigShare
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