Article thumbnail

Antibody response in hamsters immunized with recombinant LigA proteins or heat-killed leptospires (HKL).

By Mariana L. Coutinho (337710), Henry A. Choy (36168), Melissa M. Kelley (230543), James Matsunaga (230552), Jane T. Babbitt (230555), Michael S. Lewis (337711), Jose Antonio G. Aleixo (337712) and David A. Haake (36179)

Abstract

<p>Total hamster immunoglobulin responses to immunogens were measured by ELISA. Geometric mean end-point titers and standard deviations (nā€Š=ā€Š4) are shown after the first (gray), second (blue), and third (black) immunizations. In all cases, pre-immune sera were negative. Recombinant LigA proteins are represented by their domain numbers. Asterisks indicate proteins that provided 100% protection against lethal challenge.</p

Topics: Microbiology, hamsters, immunized, recombinant, liga, proteins, heat-killed, leptospires
Year: 2013
DOI identifier: 10.1371/journal.pntd.0001422.g001
OAI identifier: oai:figshare.com:article/374159
Provided by: FigShare
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • https://figshare.com/articles/... (external link)
  • Suggested articles


    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.